The Impact of Potassium Dynamics on Cardiomyocyte Beating in Hemodialysis Treatment
Hiroyuki Hamada,
Tadashi Tomo,
Sung-Teh Kim
et al.
Abstract:Background: Observational studies of intermittent hemodialysis therapy have reported that the excess decrease in K+ concentration in plasma (KP) during treatment is associated with the destabilization of cardiac function. Elucidating the mechanism by which the decrease in KP impairs myocardial excitation is indispensable for a deeper understanding of prescription design. Methods: In this study, by using an electrophysiological mathematical model, we investigated the relationship between KP dynamics and cardiom… Show more
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