The impact of peak and duration of maternal intrapartum fever on perinatal outcomes

Abstract

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Risk factors of maternal intrapartum fever and the effect of fever duration on neonatal morbidity in different temperature

“…Hochler et al found that maximal parturient temperature, solely and in combination with fever duration, had a dose–response effect on adverse neonatal outcomes while duration alone was not significantly correlated with maternal and neonatal outcomes, 10 which was partly in accordance with our findings. They suggested in case with a higher peak temperature, effort should be made to avoid long labor to minimize fetal exposure and harm, 10 however, the appropriate duration of fever was not suggested. For women with different fever peak, their encouraged time of labor may be different to reduce neonatal morbidity.…”

“…19 Ashwal et al found that the risk for adverse perinatal outcomes was also related to intrapartum fever duration, but the relationship between peak temperature and adverse neonatal outcomes was not investgated. 11 Hochler et al found that maximal parturient temperature, solely and in combination with fever duration, had a doseresponse effect on adverse neonatal outcomes while duration alone was not significantly correlated with maternal and neonatal outcomes, 10 which was partly in accordance with our findings. They suggested in case with a higher peak temperature, effort should be made to avoid long labor to minimize fetal exposure and harm, 10 however, the appropriate duration of fever was not suggested.…”

“…For women with maternal pyrexia, further evaluation was quite necessary, and obstetricians may perceive competing risks, weighing the need for operative delivery against the increasing neonatal morbidity. Although neonatal outcomes may be jointly affected by different fever peak and duration, 10,11 the analyses of the duration of fever on neonatal outcomes for women with different fever temperature were quite limited. The appropriate timing and selection of terminating delivery remained uncertain and challenging.…”

Retrospective study of intrapartum fever in term pregnancies and adverse obstetric and neonatal outcomes

“…There is increasing evidence that most intrapartum fevers arise from non-infectious etiologies, notably epidural analgesia ( Riley et al, 2011 ; Hochler et al, 2021 ). Nonetheless, notwithstanding its cause, intrapartum fever is linked to severe maternal, as well as neonatal outcomes ( Hochler et al, 2021 ).…”

“…There is increasing evidence that most intrapartum fevers arise from non-infectious etiologies, notably epidural analgesia ( Riley et al, 2011 ; Hochler et al, 2021 ). Nonetheless, notwithstanding its cause, intrapartum fever is linked to severe maternal, as well as neonatal outcomes ( Hochler et al, 2021 ). However, in some investigations, there was no remarkable link between intrapartum fever and long-term adverse events in offspring ( Towers et al, 2017 ).…”