“…This congenital abnormality represents a challenge for clinical management and should involve a multidisciplinary team experienced in the treatment of liver cancer. Dr Ayoub and Dr Jones review the "Impact of nucleos(t)ide analog therapy in hepatitis B on the incidence of hepatocellular carcinoma" [4] . Hepatitis B is a major cause of hepatocellular carcinoma worldwide, particularly in the Far East.…”