“…Secondary transmission cases represent 1-4% of all EF cases diagnosed in England every year, despite public health screening of high-risk cases and contacts. 159 These cases are presumed to have acquired EF in England either directly from an index case or carrier or via infected food. 160 Secondly, there is evidence that EF chronic carriage is an independent risk factor for gallbladder cancer, which in itself is commoner in those with gallstones.…”