The impact of multi-disciplinary intestinal rehabilitation programs on the outcome of pediatric patients with intestinal failure: A systematic review and meta-analysis

Weaning Off Prognosis Factors of Home Parenteral Nutrition for Children With Primary Digestive Disease

“…Similarly, Italian researchers (24) examining a smaller cohort during 15 years also concluded that long-term PN was a safe treatment for children with chronic IF. In addition, a systematic review and meta-analysis conducted by Canadian researchers (26) in 2013 regarding data collected during the same period as our present study showed the same improvement in the mortality rate. The multidisciplinary care program for these patients explains their better outcomes.…”

Pediatric intestinal failure: Predictors of metabolic bone disease

“…While vitamin D supplementation is commonly used in the management of children with IF, the effect of this strategy on MBD development has not been established [16]. Owing to improved medical and surgical management of IF patients, survival is far longer, though associated with prolonged PN-dependence [17][18][19]. Because of this, understanding the risk factors for MBD becomes increasingly important.…”

Visceral transplantation in patients with intestinal-failure associated liver disease: Evolving indications, graft selection, and outcomes

“…(46–50) A systematic review in 2013 established the survival advantage of the IRP, with an overall increase in patient survival by 22% and a significant reduction in septic events compared to historical controls. (51) Additional outcome measures including reduction in calories from parenteral nutrition, timely surgical and transplant evaluation, and improved coordination of care were also improved. Recent single center reports have all confirmed a decreased in mortality following the implementation of IRP with IF survival rates as high as 95% in one series.…”