The Impact of Maternal Overweight on Hair Essential Trace Element and Mineral Content in Pregnant Women and Their Children

Abstract

The aim of the present study was to investigate hair essential trace elements and mineral levels in 105 pregnant normal-weight (control) and 55 overweight and obese women in the third trimester of pregnancy, as well as in their children at the age of 9 months. The hair essential trace elements and mineral levels were assessed using inductively-coupled plasma mass-spectrometry. Overweight pregnant women had significantly reduced Cr (-24%; p = 0.047) and Zn (-13%; p = 0.008) content, as well as elevated hair Na and K levels as compared to the controls. Children from overweight and obese mothers had lower hair Mo (-18%; p = 0.017), Se (-8%; p = 0.043), and V (-24%; p = 0.028) levels, as well as elevated Sr content (19%; p = 0.025). Correlation analysis revealed a significant relationship between maternal and child hair levels of Co (r = 0.170; p=0.038), Cu (r = 0.513; p<0.001), Mn (r = 0.240; p=0.003), and Na (r = 0.181; p=0.027) in the whole sample. Pre-pregnancy maternal body mass index (BMI) positively correlated with maternal hair K (r = 0.336; p<0.001) and Na (r = 0.212; p=0.008), and negatively correlated with V (r =-0.204; p=0.011) and Zn (r =-0.162; p=0.045) levels. The results indicate that impaired trace element and mineral metabolism may play a role in the link between maternal obesity, complications of pregnancy and child's postnatal development. Hypothetically, dietary improvement may be used as a tool to reduce these risks. However, further experimental and clinical studies are required to investigate the relationship between obesity and trace element metabolism in pregnancy.

Why Do People Gain Belly Fat in Rural Areas? A Study of Urinary Metal(loid)s and Abdominal Obesity in China

“…55 This contamination is likely contributed by surrounding Pb−Zn and Mn mines. 55 Previous studies on the associations between obesity and urinary Cr have yielded inconsistent results, 24,46,56,57 suggesting indirect or insignificant association between urinary Cr levels and BMI or total body fat. WC and AOB are better indicators of visceral fat and adipose tissue, as they are more likely to accumulate metal(loid)s and are directly affected by them.…”

Первые Данные О Микроминеральных Формах Нахождения Элементов В Волосяном Покрове Млекопитающих Приморского Края

“…Исследованию волос беременных женщин и их детей, а также детей с различными заболеваниями (синдром Дауна, аутизм, синдромом дефицита внимания), проживающих на территориях вблизи вредных производств, посвящен ряд публикаций А.В. Скального c соавторами [21][22][23][24][25][26][27]. Анализу волос детей с аутизмом посвящены также работы польских и китайских ученых [28,29].…”