The impact of masticatory ability as evaluated by salivary flow rates on obesity in japanese: The Toon health study

Abstract

Objective: This study examined the associations of masticatory ability evaluated by chewing-gumstimulated salivary flow rate with anthropometric indices among a general Japanese population. Methods: In total, 921 Japanese men and women aged 30-79 years participated in this cross-sectional study. Saliva production was stimulated by 5 min of gum chewing, then collected; salivary flow rate was calculated as g/min. Overweight, abdominal obesity in terms of waist circumference (WC), and waist-hip ratio (WHR), and elevated skinfold thickness statuses were determined. Results: The multivariable odds ratio and 95% confidence intervals of overweight, abdominal obesity (WC, WHR), and elevated skinfold thickness status for highest vs. lowest quartile of salivary flow rate were 0.59 (0.37-0.95, P for trend 5 0.02), 0.65 (0.43-0.98, P 5 0.03), 0.54 (0.35-0.83, P < 0.01), and 0.61 (0.39-0.96, P < 0.01), respectively. The linear trends of multivariable-adjusted means of BMI, WC, WHR, and skinfold thickness according to quartiles of salivary flow rate did not vary after stratification by overweight status. Conclusions: Higher stimulated salivary flow rate, a surrogate marker for mastication ability, was associated with lower prevalence of overweight, abdominal obesity (whether WC-or WHR-defined), and elevated skinfold thickness among the general Japanese population.

Comparisons of Fatty Acid Taste Detection Thresholds in People Who Are Lean vs. Overweight or Obese: A Systematic Review and Meta-Analysis

“…Lower salivary flow rates have been observed in people with obesity [44–46] and it may be posited that this would diminish taste responses. However, other evidence indicates no difference in flow rates in people with and without obesity [47,48]. Both acute [17] and habitual [14] fat intake reportedly downregulate expression of NEFA receptors, which could reduce sensitivity, but evidence is based only on very preliminary data and, to be relevant, requires the unsubstantiated assumption that people with obesity necessarily select higher fat diets [21,49].…”

Factors Influencing the Changes in Masticatory Performance: The Suita Study

“…However, our previous studies are cross-sectional, and which factors affect longitudinal changes in masticatory performance have not been clarified. It is an essential issue for us to understand various factors affecting decline in masticatory performance during middle to old age because it may be a risk for diabetes (Yamazaki et al 2013), abdominal obesity (Maruyama et al 2015), and metabolic syndrome (Kikui et al 2017). If the ways in which the various factors affect long-term changes in masticatory performance were clarified, we could provide basic data for preventing or improving the decline in masticatory performance for elderly people with varying states of dentition.…”

Hubungan Status Obesitas Sentral dengan Pengalaman Karies (Indeks DMFT) pada Individu Dewasa Muda

“…18 Maruyama et al (2015) menemukan bahwa pada individu yang kelebihan berat badan memiliki flow saliva terstimulasi yang rendah. 19 20 Proinflamatori sitokin yang berasal dari adiposit tersebut dan makrofag terakumulasi pada jaringan adiposa. Kondisi tersebut memicu chronic low grade inflammation pada kelenjar saliva yang berefek pada turunnya flow saliva.…”