The Impact of Maintaining Normal Serum Albumin Level Following Living Related Liver Transplantation: Does Serum Albumin Level Affect the Course? A Pilot Study

Is replacement of albumin in major abdominal surgery useful?

“…These results are in accordance with the study of Golub and co-authors in the surgical ICU [23]. Similarly, in a recent study on the influence of albumin replacement after surgery to a target level of 30 g/L, no beneficial effect on postoperative morbidity in liver transplant surgery was observed [24]. In elderly patients after cardiac surgery, there was no difference in renal dysfunction between the group with albumin supplementation and the group given 6% hydroxyethyl starch (HES) instead of albumin; moreover, endothelial activation was even lower in the HES group [25].…”

Impact of human albumin infusion on organ function in orthotopic liver transplantation – a retrospective matched‐pair analysis

“…Moreover, Mukhtar et al. found no difference in hemodynamic variables or postoperative complications between human albumin substitution and placebo in patients undergoing living related OLT . Thus, the present study is the first to suggest reduced organ dysfunction associated with continuous substitution of human albumin in the setting of cadaveric OLT.…”

“…Hypoalbuminemia is a common finding in patients with end‐stage liver disease (ESLD) and represents an independent risk factor for mortality in these patients . It may persist even after orthotopic liver transplantation (OLT) as a sign of delayed graft function . Moreover, serum albumin concentration independently affects early kidney function and long‐term survival after OLT .…”

Uso de albumina humana em pacientes graves: controvérsias e recomendações

“…At this time, there is no apparent prognostic value in maintaining serum albumin levels above or below 3.0 mg/L. (40) It is also possible that albumin is as effective for volume resuscitation of this type of patient as HES 130/0.4 modified starch. (41) c) Trauma and postoperative Although 26% of the albumin given in the United States is targeted to acute volume loss therapy in postoperative, traumatic or hemorrhagic contexts, (6) it is not superior to crystalloids or other colloids in the context of overall postoperative volume replacement.…”