The impact of lung function case‐finding tests on smoking behaviour: A nested randomised trial within a case‐finding cohort

Abstract

Rationale, aims, and objectivesIncreasing awareness of people's lung health through the use of lung function tests or symptom‐based questionnaires is a potential method to aid smoking cessation. We investigated the impact of case‐finding lung function tests for chronic obstructive pulmonary disease on smoking behaviour.MethodsOur trial used a novel waiting list randomised controlled trial design, nested within a case‐finding cohort study. The cohort comprised current smokers aged 35 years or more, from general practices in Yorkshire and Humberside, who were randomised to receive lung function tests (spirometry, microspirometry, peak flow meter measurement, and a WheezoMeter) and case‐finding questionnaires either immediately (“tests now”) or later (“waiting list” control). Outcome measures included self‐reported smoking cessation and number of cigarettes smoked at follow‐up (at 2, 3, or 6 months after randomisation, depending on study site), with 409 participants included in the primary analysis.ResultsSix hundred seventy‐four participants were randomised using stratified block randomisation to the 2 groups (340 to “tests now” and 334 to “waiting list”), with 409 included in the primary analysis (194 in “tests now” and 215 in “waiting list” groups). Smoking cessation at follow‐up was very similar across groups (8.8% in the “tests now” group, compared with 9.2% in the “waiting list” group). Completing case‐finding lung function tests did not significantly impact smoking cessation (OR 1.00, 95% CI, 0.57‐1.77, adjusting for age, sex, baseline number of cigarettes smoked, and study site). A sensitivity analysis, assuming that participants with missing data were still smoking, gave similar results (OR 0.86, 95% CI, 0.47‐1.56). Analysis of the number of cigarettes smoked at follow‐up using negative binomial regression adjusting for the same factors above gave an incidence rate ratio of 0.95 (95% CI, 0.88‐1.03).ConclusionsThere is no evidence from this trial of an effect of lung function tests on smoking cessation among a population of smokers aged 35 years or over. Indeed, when assuming that those with missing data were smokers, a slightly lower odds of smoking cessation was observed in the “test now” group compared with the “waiting list” group.

A Fuzzy TOPSIS with Z-Number and Alpha-Cut in Identifying the Key Factor of Smoking Behaviours in Jordan

“…These four criteria were Cigars/Pipes (C1) [32]- [34]. Cigarettes (C2) [35]- [39], Chewing Tobacco in the Mouth (C4) [40]- [42]. The four criteria are choose from previous research on smoking.…”

Using pairwise randomisation to reduce the risk of bias

“…For example, a trial by Ronaldson et al used a waiting list design to assess whether having a lung health check among smokers led to a reduction in self-reported smoking. 9 In this trial, the waiting list varied from two to six months. Because the trial recruited participants from general practices (GP), which governed the waiting list length, the GP was included in the statistical model to account for variation in follow-up time.…”