The Impact of Lower Urinary Tract Symptoms on Quality of Life, Work Productivity, Depressive Symptoms, and Sexuality in Korean Men Aged 40 Years and Older: A Population-Based Survey

Abstract

Purpose:To examine the impact of lower urinary tract symptoms (LUTS) on health-related quality of life (HRQoL) in Korean men aged ≥40 years.Methods:A population-based, cross-sectional door-to-door survey was conducted among men aged ≥40 years. Individuals with LUTS were defined as men reporting at least one LUTS using 2002 International Continence Society definitions. Structuredquestionnaires were used to assess several dimensions of HRQoL, including generic health status (EuroQoL-five-dimensions questionnaire), work productivity (work productivity and activity impairment questionnaire), depressive symptoms (center for epidemiologic studies depression scale), and sexual health (sexual satisfaction and erectile dysfunction). The impact of LUTS was assessed by comparing several dimensions of HRQoL among men with and without LUTS.Results:Of the 1,842 participants, 1,536 (83.4%) reported having at least one LUTS. The prevalence of LUTS increased with age (78.3% among those aged 40–49 years to 89.6% among those aged 60 years or older). Those with LUTS reported a significantlylower level of generic health status and worse work productivity compared with those without LUTS. Significantly more individuals with LUTS reported having a higher level of major depressive symptoms compared with those without LUTS.Those with LUTS reported worse sexual activity and enjoyment, and were significantly more likely to have erectile dysfunction than those without LUTS.Conclusions:LUTS seem to have a substantial impact on several dimensions of HRQoL in Korean men aged ≥40 years.

Impact of lower urinary tract symptoms on work productivity in female workers: A systematic review and meta‐analysis

“…However, our results need to be interpreted with caution as we did not find evidence that absenteeism was associated with reduced work productivity although a significant difference in absenteeism was found between LUTS and control groups in one study . This is in line with previous studies, which reported that health conditions including LUTS impact more strongly on presenteeism than on absenteeism in males and mixed‐sex populations . Although risk factors associated with reduced work productivity have been identified in other patient populations, there is limited evidence on the risk factors in female workers with LUTS.…”

The global prevalence of erectile dysfunction: a review

“…Men with ED are 1.33-6.24-times more likely to have BPH than men without ED [18,23,[31][32][33]35,57,[61][62][63] (Appendix S2 [14,18,23,[31][32][33]35,56,61,62,64,65]). Prevalence of ED and BPH ranged from 5.2% to 40% [64,65] and prevalence was positively associated with increasing age [64].…”

Persistence of solifenacin therapy in patients with overactive bladder in the clinical setting: a prospective, multicenter, observational study

“…It is defined as urinary urgency with or without urgency urinary incontinence and is usually associated with increased daytime frequency and nocturia (3). OAB has considerable impact on health-related quality of life (4)(5)(6)(7)(8).…”