2021
DOI: 10.1177/0961203320988595
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The impact of low muscle function on health-related quality of life in Indonesian women with systemic lupus erythematosus

Abstract: Objective There was no study aimed at evaluating the effect of muscle function on SLE patients' quality of life using the Sarcopenia Quality of Life (SarQoL) questionnaire. Methods This cross-sectional study recruited 61 women with SLE consecutively, muscle function was measured with Jamar handheld-dynamometer and 6-meter walk test, HRQoL was measured with Sarcopenia Quality of Life (SarQoL) questionnaire. The cut-off point for low muscle strength (<18 kg) and low gait speed (<1.0 m/s) was according to t… Show more

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Cited by 6 publications
(6 citation statements)
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“…Pulse dose corticosteroids 500–1000 mg IV per day is given for 3–5 days in severe disease activity for faster disease control. Cyclophosphamide is given 500 mg every 2 weeks, 6 doses, or 500–1000 mg/m 2 monthly for 6 months, while cyclophosphamide is given in severe lupus [15] , [16] .…”
Section: Discussionmentioning
confidence: 99%
“…Pulse dose corticosteroids 500–1000 mg IV per day is given for 3–5 days in severe disease activity for faster disease control. Cyclophosphamide is given 500 mg every 2 weeks, 6 doses, or 500–1000 mg/m 2 monthly for 6 months, while cyclophosphamide is given in severe lupus [15] , [16] .…”
Section: Discussionmentioning
confidence: 99%
“…The group of patients defined as having low HGS was found to be 44%, and the sarcopenia quality of life indices were reported to be lower in the low HGS group. 11 The relationship between sarcopenia and disease markers has been extensively studied in other rheumatic diseases such as osteoarthritis, rheumatoid arthritis, systemic sclerosis, Sjögren's syndrome and ankylosing spondylitis. However, little is known about the relationship between SLE-specific markers and sarcopenia.…”
Section: Diṡcussiȯnmentioning
confidence: 99%
“…9 Interestingly, although many studies in the autoimmune population have shown an increased rate of sarcopenia in the affected subjects, there is still a debate on what is more important, muscle function or strength, in its impact on HRQoL. 10 Following our previous study, 8 we evaluate the impact of muscle function (strength) and muscle mass on SarQoL to better understand the issue in patients with lupus. In addition, we also try to determine associated factors affecting muscle strength to help further intervention in increasing the quality of life of patients with lupus.…”
Section: How This Study Might Affect Research Practice or Policymentioning
confidence: 99%
“… 4–7 Our previous study has also established that low muscle strength significantly impacts sarcopenia health-related quality of life (SarQoL) in Indonesian women with lupus. 8 Our study used the SarQoL Questionnaire to evaluate HRQoL because, unlike generic HRQoL tools, SarQoL specifically measures the specific domains directly related to muscle strength and function. 9 …”
Section: Introductionmentioning
confidence: 99%
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