The impact of intraoperative culture on treatment and outcome in children with perforated appendicitis

Streptococcus milleri in intraabdominal abscesses in children after appendectomy: incidence and course

“…In various studies S milleri was present in microbiological cultures taken during surgery in 20% to 61% of patients with acute appendicitis [6,13,14]. However, not all studies that describe intraabdominal bacteriology at appendectomy make notice of S milleri [5,15,16]. In our study, 7% of the children developed an intraabdominal abscess after appendectomy despite prophylactic cephalosporin and metronidazole given at surgery and postoperative treatment with antibiotics in cases of perforated appendicitis.…”

Are routine peritoneal fluid cultures during appendicectomy justified?

“…Jeffers and Pollock [12] have previously noted that in 608 patients with acute appendicitis, not a single patient had antibiotic therapy changed on the basis of culture results. Other studies have observed that culture findings can influence a change of antibiotic treatment in 7-16% of patients [9,13]. Antibiotics were modified in three patients on clinical grounds in this study.…”

Peritoneal fluid culture and antibiotic treatment in patients with perforated appendicitis in a Pacific Island

“…11,13 A wide variation of positive culture rate has previously been described, ranging from 24% to 93%, 10,14,15 most likely explained by the various techniques employed for collection and transfer of specimens and culture.…”