“…After FMT, the numbers of Bifidobacteria and Escherichia coli increased, and with an increase in Firmicutes and a decrease in Bacteroides increasing the F/B ratio along with an increase in floral diversity, the distribution of gut microbiota approached normal ( de Groot et al., 2021 ; He et al., 2022 ; Xie et al., 2022 ). Although T1DM is an autoimmune disease, patients may exhibit abnormal plasma metabolism ( Zheng et al., 2022 ). In a longitudinal study, the early development of T1DM in infants was associated with reduced levels of sugar derivatives, amino acids, and fatty acids (including SCFAs), compared with controls ( Huang et al., 2020 ).…”