2020
DOI: 10.1055/s-0040-1710552
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The Impact of Indocyanine-Green Fluorescence Angiography on Intraoperative Decision-Making and Postoperative Outcome in Free Flap Surgery

Abstract: Background Reliable perfusion of the distal portions of free flaps is decisive for the reconstructive success. Indocyanine green near-infrared video angiography (ICG-NIR-VA) has been adopted for objective assessment of free flap tissue perfusion but is thus far not used on a routine basis. Therefore, we investigated its intraoperative impact on decision-making and postoperative outcome. Methods From January 2017 to June 2019, 88 consecutive adipo- or fasciocutaneus free flaps were performed in conjun… Show more

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Cited by 24 publications
(36 citation statements)
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References 27 publications
(61 reference statements)
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“…39 Moreover, ICG, owing to its high sensitivity, specificity, and positive predictive value of tissue necrosis, has been shown to increase the rate of survival of different free flaps by refining surgical decision-making on flap design. 40 Additionally, the use of ICG has shown to predict possible internal jugular vein (IJV) thrombosis intraoperatively after free flaps anastomosis by reporting greater venous flow rates and subsequent ICG fluorescence time (reaching 18 seconds) than expected. 28 In a study on free jejunum transfer after circumferential pharyngolaryngectomy, it was highlighted that the value of postoperative monitoring of buried free flaps after wound closure is more predictive than intraoperative monitoring in identifying vascular compromise.…”
Section: Icg Angiography: Results By Indication and Type Of Flap Freementioning
confidence: 99%
“…39 Moreover, ICG, owing to its high sensitivity, specificity, and positive predictive value of tissue necrosis, has been shown to increase the rate of survival of different free flaps by refining surgical decision-making on flap design. 40 Additionally, the use of ICG has shown to predict possible internal jugular vein (IJV) thrombosis intraoperatively after free flaps anastomosis by reporting greater venous flow rates and subsequent ICG fluorescence time (reaching 18 seconds) than expected. 28 In a study on free jejunum transfer after circumferential pharyngolaryngectomy, it was highlighted that the value of postoperative monitoring of buried free flaps after wound closure is more predictive than intraoperative monitoring in identifying vascular compromise.…”
Section: Icg Angiography: Results By Indication and Type Of Flap Freementioning
confidence: 99%
“…Image-guided surgeries, performed after injecting ICG dye into blood vessels, have been used to delineate the cancer margin in urology, hepatobiliary, and colorectal surgery, as well as to explore sentinel nodes; there are also reports of robots being used in monitoring the flap pedicle (38)(39)(40). Da Vinci's camera has a built-in Near Infrared (NIR) system which can be activated simply by finger trigger.…”
Section: Discussionmentioning
confidence: 99%
“…As in our case, perfusion in the distal part of the flap can be unreliable, and the extent of the potentially ischemic flap in need of resection is unknown in the absence of techniques such as ICG angiography. ICG allows for intraoperative decision-making when determining flap viability [19]. As a result, intraoperative ICG for muscle flaps has the potential to decrease the length of individual hospital stays and thus associated economic costs.…”
Section: Discussionmentioning
confidence: 99%