The Impact of Hydrogen Peroxide (H2O2) Fumigation on Bacterial Levels in Dental Office Environments: A Randomized Clinical Trial Investigation

Matys, Jacek; Gedrange, Tomasz; Dominiak, Marzena; Grzech-Leśniak, Kinga

doi:10.3390/jcm12247551

Cited by 2 publications

(1 citation statement)

References 44 publications

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“…The effectiveness of fumigation is highly dependent on the materials to be disinfected (54,56), e.g., the effect of fogged peracetic acid and hydrogen peroxide was shown to be particularly high on glass windows and doors, and low on fabric materials (56). Further, the efficacy depends on the type of microorganism, the fumigation device and technology and the substance (57)(58)(59). One downfall of the fumigation of chemicals is the safety measures, that have to be ensured.…”

Section: Fumigation Of Chemicals As An Antimicrobial Approachmentioning

confidence: 99%

An overview of the bacterial microbiome of public transportation systems—risks, detection, and countermeasures

Ly,

Leuko,

Moeller

2024

Front. Public Health

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When we humans travel, our microorganisms come along. These can be harmless but also pathogenic, and are spread by touching surfaces or breathing aerosols in the passenger cabins. As the pandemic with SARS-CoV-2 has shown, those environments display a risk for infection transmission. For a risk reduction, countermeasures such as wearing face masks and distancing were applied in many places, yet had a significant social impact. Nevertheless, the next pandemic will come and additional countermeasures that contribute to the risk reduction are needed to keep commuters safe and reduce the spread of microorganisms and pathogens, but also have as little impact as possible on the daily lives of commuters. This review describes the bacterial microbiome of subways around the world, which is mainly characterized by human-associated genera. We emphasize on healthcare-associated ESKAPE pathogens within public transport, introduce state-of-the art methods to detect common microbes and potential pathogens such as LAMP and next-generation sequencing. Further, we describe and discuss possible countermeasures that could be deployed in public transportation systems, as antimicrobial surfaces or air sterilization using plasma. Commuting in public transport can harbor risks of infection. Improving the safety of travelers can be achieved by effective detection methods, microbial reduction systems, but importantly by hand hygiene and common-sense hygiene guidelines.

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Section: Fumigation Of Chemicals As An Antimicrobial Approachmentioning

confidence: 99%

An overview of the bacterial microbiome of public transportation systems—risks, detection, and countermeasures

Ly,

Leuko,

Moeller

2024

Front. Public Health

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New Insights Regarding the Use of Relevant Synthetic Compounds in Dentistry

Dumitrel,

Matichescu,

Dinu

et al. 2024

Molecules

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Worldwide, synthetic compounds are used for both in-office and at-home dental care. They are a valuable resource for both prophylactic and curative treatments for various dental problems, such as tooth decay, periodontal diseases, and many more. They are typically preferred due to their broad range of actions and ability to produce targeted, rapid, and long-lasting effects. Using a 0.12% chlorhexidine mouthwash is capable of reducing the plaque index from 47.69% to 2.37% and the bleeding index from 32.93% to 6.28% after just 2 weeks. Mouthwash with 0.1% OCT is also highly effective, as it significantly lowered the median plaque index and salivary bacterial counts in 152 patients in 5 days compared to a control group (p < 0.0001), while also reducing the gingival index (p < 0.001). When povidone-iodine was used as an irrigant during the surgical removal of mandibular third molars in 105 patients, it resulted in notably lower pain scores after 2 days compared to a control group (4.57 ± 0.60 vs. 5.71 ± 0.45). Sodium hypochlorite is excellent for root canal disinfection, as irrigating with 1% NaOCl completely eliminated the bacteria from canals in 65% patients. A 0.05% CPC mouthwash proved effective for perioperative patient care, significantly decreasing gingival bleeding (p < 0.001) and suppressing Streptococcus levels even one week post-surgery. Lastly, a 6% H2O2 paint-on varnish and 6% H2O2 tray formulations successfully bleached the teeth of 40 patients, maintaining a noticeably whiter appearance up to the 6-month follow-up, with significant color differences from the baseline (p < 0.005). Synthetic compounds have a large research base, which also provides a greater awareness of their mechanism of action and potential adverse effects. For a better understanding of how they work, several methods and assays are performed. These are protocolary techniques through which a compound’s efficacy and toxicity are established.

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The Impact of Hydrogen Peroxide (H2O2) Fumigation on Bacterial Levels in Dental Office Environments: A Randomized Clinical Trial Investigation

Cited by 2 publications

References 44 publications

An overview of the bacterial microbiome of public transportation systems—risks, detection, and countermeasures

An overview of the bacterial microbiome of public transportation systems—risks, detection, and countermeasures

New Insights Regarding the Use of Relevant Synthetic Compounds in Dentistry

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