The Impact of Hepatitis C on Complication Rates After Revision Total Knee Arthroplasty: A Matched Cohort Study

Ross, Bailey J.; Ross, Austin J.; Cole, Matthew W.; Guild, George N.; Lee, Olivia; Sherman, William F.

doi:10.1016/j.artd.2022.09.010

Cited by 5 publications

(2 citation statements)

References 48 publications

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“…[40][41][42][43][44] Similarly, in the absence of liver-related complications, HCV infection does not seem to confer a greater risk for postoperative complications for most procedures, though PLWHCV may have worse outcomes for some elective orthopedic surgeries. [45][46][47] There are several possible explanations for our findings. First, patients with HIV and HCV may face barriers to accessing health care and hence present later in their disease process.…”

Section: Discussionmentioning

confidence: 88%

“…These low surgical intervention rates are notable in light of studies of several types of surgery—including cardiac surgery, EGS, and spine surgery—that have shown equivalent rates of serious complications and operative mortality for patients living with and without HIV 40–44 . Similarly, in the absence of liver-related complications, HCV infection does not seem to confer a greater risk for postoperative complications for most procedures, though PLWHCV may have worse outcomes for some elective orthopedic surgeries 45–47 …”

Section: Discussionmentioning

confidence: 99%

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HIV and Hepatitis C Virus-Related Disparities in Undergoing Emergency General Surgical Procedures in the United States, 2016-2019

et al. 2023

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Objective: To determine whether people living with human immunodeficiency virus (PLWHIV) and people living with hepatitis C virus (PLWHCV) experience inequities in receipt of emergency general surgery (EGS) care. Background: PLWHIV and PLWHCV face discrimination in many domains; it is unknown whether this extends to the receipt of EGS care. Methods: Using data from the 2016 to 2019 National Inpatient Sample, we examined 507,458 nonelective admissions of adults with indications for one of the 7 highest-burden EGS procedures (partial colectomy, small-bowel resection, cholecystectomy, operative management of peptic ulcer disease, lysis of peritoneal adhesions, appendectomy, or laparotomy). Using logistic regression, we evaluated the association between HIV/HCV status and the likelihood of undergoing one of these procedures, adjusting for demographic factors, comorbidities, and hospital characteristics. We also stratified analyses for the 7 procedures separately. Results: After adjustment for covariates, PLWHIV had lower odds of undergoing an indicated EGS procedure [adjusted odds ratio (aOR): 0.81; 95% CI: 0.73-0.89], as did PLWHCV (aOR: 0.66; 95% CI: 0.63-0.70). PLWHIV had reduced odds of undergoing cholecystectomy (aOR: 0.68; 95% CI: 0.58-0.80). PLWHCV had lower odds of undergoing cholecystectomy (aOR: 0.57; 95% CI: 0.53-0.62) or appendectomy (aOR: 0.76; 95% CI: 0.59-0.98). Conclusions: PLWHIV and PLWHCV are less likely than otherwise similar patients to undergo EGS procedures. Further efforts are warranted to ensure equitable access to EGS care for PLWHIV and PLWHCV.

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