The impact of essential oils on antibiotic use in animal production regarding antimicrobial resistance – a review

Evangelista, Alberto Gonçalves; Corrêa, Jessica Audrey Feijó; Pinto, Anne Caroline Schoch Marques; Luciano, Fernando Bittencourt

doi:10.1080/10408398.2021.1883548

Cited by 45 publications

(36 citation statements)

References 177 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These results were different from the results obtained in previous studies [ 35 , 119 , 120 , 121 ]. The prevalence of aadA (75%) and tet(A) (50%) genes in E. coli O157 isolates [ 122 ] and blaTEM (66.6%) and tet(B 66.6%) genes in Salmonella isolates ( Figure S2 ) were lower than the detected prevalence by McMillan et al [ 123 ], whereas the detected prevalence of penA (50%), ampC (66.6%), and ermB (28%) genes in L. monocytogenes isolates is higher in our study than the detected prevalence of the same genes in fecal and environmental samples collected from Tennessee [ 35 , 124 ]. Further, the prevalence of blaOXA-61 (90%) and tet(O) (79%) in Campylobacter isolates is higher than their prevalence in fecal samples collected from northwestern Ohio and Michigan [ 71 , 82 ].…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Antimicrobial Resistance Profiles of Foodborne Pathogens Isolated from Dairy Cattle and Poultry Manure Amended Farms in Northeastern Ohio, the United States

et al. 2021

View full text Add to dashboard Cite

Foodborne pathogens significantly impact public health globally. Excessive antimicrobial use plays a significant role in the development of the public health crisis of antibiotic resistance. Here, we determined the prevalence and antimicrobial resistance profiles of E. coli O157, Salmonella, L. monocytogenes, and Campylobacter isolated between 2016 and 2020 from small scale agricultural settings that were amended with dairy cattle or poultry manure in Northeastern Ohio. The total prevalence of the foodborne pathogens was 19.3%: Campylobacter 8%, Listeria monocytogenes 7.9%, Escherichia coli O157 1.8%, and Salmonella 1.5%. The prevalence was significantly higher in dairy cattle (87.7%) compared to poultry (12.2%) manure amended farms. Furthermore, the prevalence was higher in manure samples (84%) compared to soil samples (15.9%; p < 0.05). Multiple drug resistance was observed in 73%, 77%, 100%, and 57.3% of E. coli O157, Salmonella, L. monocytogenes, and Campylobacter isolates recovered, respectively. The most frequently observed resistance genes were mphA, aadA, and aphA1 in E. coli O157; blaTEM, tet(B), and strA in Salmonella; penA, ampC, lde, ermB, tet(O), and aadB in L. monocytogenes and blaOXA-61, tet(O), and aadE in Campylobacter. Our results highlight the critical need to address the dissemination of foodborne pathogens and antibiotic resistance in agricultural settings.

show abstract

Section: Discussionmentioning

confidence: 99%

Prevalence and Antimicrobial Resistance Profiles of Foodborne Pathogens Isolated from Dairy Cattle and Poultry Manure Amended Farms in Northeastern Ohio, the United States

et al. 2021

View full text Add to dashboard Cite

show abstract

“… Brenes and Roura (2010) showed that the antimicrobial mechanism of essential oils is largely depended on their hydrophobic property, which disrupts the structure and permeability of cells. Besides, essential oils can prevent the development of antimicrobial resistance by replacing conventional antibiotics in animal production, and when used as antibiotic adjuvants, they can help control bacteria that have developed resistance through regulating genes associated with resistance mechanisms ( Evangelista et al, 2021 ), which in turn reduce human and animal infections by resistant pathogens. Thus, the organic acids have potential as possible alternatives to antibiotics in the poultry farming.…”

Section: Introductionmentioning

confidence: 99%

Regulatory Effects of Combined Dietary Supplementation With Essential Oils and Organic Acids on Microbial Communities of Cobb Broilers

et al. 2022

View full text Add to dashboard Cite

The emergence and spread of antibiotic resistance genes in pathogenic microorganisms have resulted in many countries restricting the use of antibiotics as growth promoters in animal feed. The combined use of essential oils and organic acids can help maintain intestinal health, improve animal growth performance, and alleviate the negative effects of banned antibiotics for certain economically important animals. Although the modes of action for the combined dietary supplementation of essential oils and organic acids such as thymol-citric acid (EOA1) and thymol-butyric acid (EOA2) remain unclear, it is speculated that their activities are achieved through beneficial modulation of gastrointestinal microbial communities and inhibition of pathogen growth. In this study, 16S rDNA amplicon sequencing was used to analyze the effects of treatment with EOA1 and EOA2 on the jejunal, cecal, and fecal microbial communities of Cobb broilers while also evaluating effects over different broiler ages. The intestinal microbial communities of broilers developed with increasing age, and Lactobacillus gradually came to dominate the intestinal communities of treated broilers. Further, the microbial communities of feces were more complex than those of the jejuna and ceca. We systematically elucidate that the longitudinal changes in the intestinal microbial communities of Cobb broiler chickens at different ages. Meanwhile, we found that the addition of EOA1 or EOA2 to the diet: (1) inhibited the proliferation of Ralstonia pickettii and Alcaligenaceae in the jejuna on day 28, (2) promoted the colonization and growth of beneficial bacteria such as Lactobacillus, Clostridia, and Bacteroidia at various growth stages, and (3) enriched the abundance of certain microbiota functions, including biological pathways related to metabolism (e.g., enzyme families). Taken together, the results of this study demonstrate that EOA1 and EOA2 dietary supplementation can affect various microbial metabolic pathways related to the metabolism and absorption of nutrients via regulation of the intestinal microbial community structures of Cobb broilers.

show abstract

“…However, with pungent taste and odor, methods are necessary to enable its application in food and raw materials. Cinnamaldehyde (CIN) is a compound isolated from the essential oil of plants belonging to the Cinnamomum genus, which possess proven antibacterial, antifungal, and antimycotoxigenic properties (Bravo Cadena et al., 2018; Evangelista et al., 2021; Muller et al., 2017; Mutlu‐Ingok et al., 2020; Shreaz et al., 2016). With pleasant sensory acceptance to animals and humans, it may be a viable alternative for joint application with AITC.…”

Section: Introductionmentioning

confidence: 99%

Combination of allyl isothiocyanate and cinnamaldehyde against the growth of mycotoxigenic fungi and aflatoxin production in corn

Evangelista

Bocate

Meca

et al. 2021

J. Food Process. Preserv.

Self Cite

View full text Add to dashboard Cite

In this report, cinnamaldehyde (CIN) and allyl isothiocyanate (AITC) were combined against mycotoxigenic fungi. Minimum inhibitory concentrations (MIC) and interaction between compounds were evaluated in culture media, and gas‐phase inhibition and aflatoxin yield were evaluated in corn. Doses of 0.076, 0.605, and 0.303 mM of AITC, and 0.246, 1.964, and 0.982 mM of CIN were the MIC for Aspergillus parasiticus, Fusarium verticillioides, and Fusarium graminearum, respectively. Together, 0.038 mM of AITC and 0.061 mM of CIN were required to inhibit A. parasiticus; 0.038 and 1.964 mM to F. verticillioides; and 0.076 and 0.246 mM to F. graminearum. In gas‐phase, 0.62, 0.47, and 0.23 μl/L (1:5 AITC:CIN) inhibited A. parasiticus, F. verticillioides, and F. graminearum in Petri dishes, respectively. In corn, 300 μl/L (1:5 AITC:CIN) reduced the fungal population below the detection limit. The use of AITC + CIN significantly reduced aflatoxins production. Therefore, these compounds may be an alternative to avoid contamination. Novelty impact statement AITC and CIN may be used against contamination of mycotoxigenic fungi, and they have the potential to inhibit aflatoxins production. AITC is very pungent and the combination with CIN can mask the strong odor of the former compound. Therefore, these compounds can be combined to reduce production losses.

show abstract

The impact of essential oils on antibiotic use in animal production regarding antimicrobial resistance – a review

Cited by 45 publications

References 177 publications

Prevalence and Antimicrobial Resistance Profiles of Foodborne Pathogens Isolated from Dairy Cattle and Poultry Manure Amended Farms in Northeastern Ohio, the United States

Prevalence and Antimicrobial Resistance Profiles of Foodborne Pathogens Isolated from Dairy Cattle and Poultry Manure Amended Farms in Northeastern Ohio, the United States

Regulatory Effects of Combined Dietary Supplementation With Essential Oils and Organic Acids on Microbial Communities of Cobb Broilers

Combination of allyl isothiocyanate and cinnamaldehyde against the growth of mycotoxigenic fungi and aflatoxin production in corn

Contact Info

Product

Resources

About