The impact of EGFR T790M mutation status following the development of Osimertinib resistance on the efficacy of Osimertinib in non‐small cell lung cancer: A meta‐analysis
Liuxian Guo,
Guojin Zhou,
Min Huang
et al.
Abstract:BackgroundPrevious studies have suggested that loss of the EGFR T790M gene mutation may contribute to the development of resistance to Osimertinib in non‐small cell lung cancer (NSCLC).AimsThis study aims to assess the relationship between the clinical effectiveness of Osimertinib in NSCLC patients and the T790M mutation status following resistance to Osimertinib and examine differences between plasma and tissue tests and between Asian and non‐Asian groups.MethodsThe PubMed, Web of Science, Cochrane, and EMBAS… Show more
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