The impact of dysfunctional breathing on the level of asthma control in difficult asthma

Sedeh, Farnam Barati; Bülow, Anna Von; Backer, Vibeke; Bødtger, Uffe; Petersen, Ulrik Søes; Vest, Susanne; Hull, James H.; Porsbjerg, Celeste

doi:10.1016/j.rmed.2020.105894

Cited by 18 publications

(22 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Dysfunctional breathing has been studied extensively in poorly controlled asthma ( 147 ) because it is common and is associated with significantly poor asthma control and lower quality of life. Evidence-based guidelines recommend breathing retraining interventions as adjuvant treatment in uncontrolled asthma.…”

Section: Mg In Specific Patient Groupsmentioning

confidence: 99%

A Practical Approach to Managing Patients With Myasthenia Gravis—Opinions and a Review of the Literature

Farrugia

Goodfellow

2020

Front. Neurol.

View full text Add to dashboard Cite

When the diagnosis of myasthenia gravis (MG) has been secured, the aim of management should be prompt symptom control and the induction of remission or minimal manifestations. Symptom control, with acetylcholinesterase inhibitors such as pyridostigmine, is commonly employed. This may be sufficient in mild disease. There is no single universally accepted treatment regimen. Corticosteroids are the mainstay of immunosuppressive treatment in patients with more than mild MG to induce remission. Immunosuppressive therapies, such as azathioprine are prescribed in addition to but sometimes instead of corticosteroids when background comorbidities preclude or restrict the use of steroids. Rituximab has a role in refractory MG, while plasmapheresis and immunoglobulin therapy are commonly prescribed to treat MG crisis and in some cases of refractory MG. Data from the MGTX trial showed clear evidence that thymectomy is beneficial in patients with acetylcholine receptor (AChR) antibody positive generalized MG, up to the age of 65 years. Minimally invasive thymectomy surgery including robotic-assisted thymectomy surgery has further revolutionized thymectomy and the management of MG. Ocular MG is not life-threatening but can be significantly disabling when diplopia is persistent. There is evidence to support early treatment with corticosteroids when ocular motility is abnormal and fails to respond to symptomatic treatment. Treatment needs to be individualized in the older age-group depending on specific comorbidities. In the younger age-groups, particularly in women, consideration must be given to the potential teratogenicity of certain therapies. Novel therapies are being developed and trialed, including ones that inhibit complement-induced immunological pathways or interfere with antibody-recycling pathways. Fatigue is common in MG and should be duly identified from fatigable weakness and managed with a combination of physical therapy with or without psychological support. MG patients may also develop dysfunctional breathing and the necessary respiratory physiotherapy techniques need to be implemented to alleviate the patient's symptoms of dyspnoea. In this review, we discuss various facets of myasthenia management in adults with ocular Farrugia and Goodfellow Practical Approaches to Myasthenia Management and generalized disease, including some practical approaches and our personal opinions based on our experience.

show abstract

Section: Mg In Specific Patient Groupsmentioning

confidence: 99%

A Practical Approach to Managing Patients With Myasthenia Gravis—Opinions and a Review of the Literature

Farrugia

Goodfellow

2020

Front. Neurol.

View full text Add to dashboard Cite

show abstract

“…Our sample size was small and predominantly female. We found high rates (21/30, 70%) of positive BPAT scores (score ≥4), compared to previously published proportions in a similar population (29/117, 25%) 10 . Participants in this investigation were aware that their breathing pattern was being observed and video recorded.…”

Section: In‐person Assessment In‐person and Video Assessment In‐person And Video Assessment (No Sound Scores)mentioning

confidence: 41%

Reliability of the breathing pattern assessment tool for in‐person or remote assessment in people with asthma

Bondarenko

Hew

Button

et al. 2021

Clin Experimental Allergy

View full text Add to dashboard Cite

“…It can be defined as an alteration in the normal biomechanical pattern of breathing, leading to intrusive symptoms49 that can impact athletic performance and quality of life 50. BPD can occur in the presence or absence of other comorbidities, including EIB, EILO and/or anxiety, and in this context can act to overlap or amplify symptoms and make them appear ‘treatment resistant’ 51. It is vital that any other condition or comorbidity is detected, considered and optimised prior to assuming an athlete’s symptoms are fully explained by BPD.…”

Section: Introductionmentioning

confidence: 99%

BTS clinical statement for the assessment and management of respiratory problems in athletic individuals

Hull

Burns

Carre

et al. 2022

Thorax

View full text Add to dashboard Cite

The impact of dysfunctional breathing on the level of asthma control in difficult asthma

Cited by 18 publications

References 37 publications

A Practical Approach to Managing Patients With Myasthenia Gravis—Opinions and a Review of the Literature

A Practical Approach to Managing Patients With Myasthenia Gravis—Opinions and a Review of the Literature

Reliability of the breathing pattern assessment tool for in‐person or remote assessment in people with asthma

BTS clinical statement for the assessment and management of respiratory problems in athletic individuals

Contact Info

Product

Resources

About