The impact of disease severity on EQ-5D and SF-6D utility discrepancies in chronic heart failure

Kontodimopoulos, Nick; Argiriou, Mihalis; Theakos, Nikolaos; Niakas, Dimitris

doi:10.1007/s10198-010-0252-4

Cited by 30 publications

(25 citation statements)

References 47 publications

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“…As shown in Supplemental Content 4, http://links.lww.com/CCM/B175), the EQ-5D scores for frail survivors in our study were lower than those reported in the literature for several chronic diseases (35)(36)(37)(38). Similarly, the EQ-5D scores for frail survivors were also markedly lower when compared with scores reported by ICU survivors (10,30,39).…”

Section: Association Of Chronic Disease Critical Illness Syndromes contrasting

confidence: 82%

See 1 more Smart Citation

Long-Term Association Between Frailty and Health-Related Quality of Life Among Survivors of Critical Illness

Bagshaw

Stelfox

Johnson

et al. 2015

Critical Care Medicine

204

149

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show abstract

Section: Association Of Chronic Disease Critical Illness Syndromes contrasting

confidence: 82%

“…Prehospital frailty (CFS > 4) was present in 33% (n = 138; 95% CI, [28][29][30][31][32][33][34][35][36][37][38]. Baseline characteristics stratified by frailty are shown in Table 1.…”

Section: Characteristics and Outcomes Of Frail Patientsmentioning

confidence: 99%

Long-Term Association Between Frailty and Health-Related Quality of Life Among Survivors of Critical Illness

Bagshaw

Stelfox

Johnson

et al. 2015

Critical Care Medicine

204

149

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“…In 2011, Soler et al reported the first prospective study evaluating utility outcomes following ESS for patients with refractory CRS . Using the SF‐6D health‐state utility questionnaire, they demonstrated a baseline CRS utility value of 0.65 (95% confidence interval, 0.63‐0.66), which was lower than other chronic conditions such as congestive heart failure and chronic obstructive pulmonary disease . With a mean follow‐up of 1.5 years after ESS, the utility score increased by 0.087 (95% confidence interval, 0.06 −0.12) to provide a mean overall short‐term post‐ESS utility value of 0.74.…”

Section: Discussionmentioning

confidence: 99%

Long‐term utility outcomes in patients undergoing endoscopic sinus surgery

et al. 2013

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Objective To define long-term health state utility outcomes in patients undergoing endoscopic sinus surgery (ESS) for refractory chronic rhinosinusitis (CRS) Study Design Prospective, longitudinal cohort study Methods The SF-12 survey was issued to the 168 patients who were enrolled in an initial study evaluating short-term utility outcomes following ESS. SF-12 responses were converted into SF-6D utility scores using the University of Sheffield algorithm. The primary outcome was mean overall long-term utility level following ESS. Secondary outcomes evaluated annual utility level following ESS and utility outcomes for different subgroups of patients with CRS. Results A total of 83 patients provided long-term health state utility outcomes. The mean overall long-term utility level was 0.80 at a mean follow-up of 5.2 years after ESS. Compared to the baseline (0.67) and short-term follow-up (0.75) utility levels in this group, there was a significant improvement at the long-term period (p=0.002). 54% (45/83) of patients achieved long-term postoperative utility scores higher than the United States (US) norm of 0.81. There was a significant improvement in utility scores for all subsequent years after ESS compared to preoperative responses (all p<0.028). All subgroups of CRS received significant long-term utility improvements (all p<0.001), while those undergoing revision ESS demonstrated continued improvement past the short-term postoperative period. Conclusion This study has demonstrated that patients with refractory CRS achieve stable mean long-term utility levels following ESS and often return to a health state comparable to US population norms.

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“…If the same association between SES and HRQL could also be found among patients with diabetes mellitus, for example, this would clearly indicate two potential problems: health inequalities would be underestimated if HRQL is not assessed, and policy recommendations based on HRQL analyses could be biased if the differences according to SES are not stressed. Although not primarily devoted to the investigation of SES, most of these studies include SES in the analysis of HRQL, looking at a specific group of patients such as patients with heart attack [34], myocardial infarction [35], type 2 diabetes [36], chronic low back pain [37], chronic obstructive pulmonary disease (COPD) [38], depression [39] or patients undergoing elective cardiac surgery [40] or percutaneous coronary intervention (PCI) [41]. Other studies are based on population surveys including different chronic diseases [33,42,43].…”

Section: Introductionmentioning

confidence: 99%

“…Some report that the positive association between SES and HRQL is significant either for men or for women or for specific indicators of SES [37]. Others show that this association is significant only for the EQ-5D-3 L time trade-off (TTO) valuation, but not for the EQ-5D-3 L Visual Analog Scale (VAS) [40]. Some indicate that this association is not statistically significant [39], and some do not even include a statistical test for this association [33,42].…”

Section: Introductionmentioning

confidence: 99%

Health-related quality of life and socioeconomic status: inequalities among adults with a chronic disease

Mielck

Vogelmann²,

Leidl

2014

Health Qual Life Outcomes

169

112

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BackgroundA number of studies have shown an association between health-related quality of life (HRQL) and socioeconomic status (SES). Indicators of SES usually serve as potential confounders; associations between SES and HRQL are rarely discussed in their own right. Also, few studies assess the association between HRQL and SES among those with a chronic disease. The study focuses on the question of whether people with the same state of health judge their HRQL differently according to their SES, and whether a bias could be introduced by ignoring these differences.MethodsThe analyses were based on a representative sample of the adult population in Germany (n = 11,177). HRQL was assessed by the EQ-5D-3 L, i.e. the five domains (e.g. ‘moderate or severe problems’ concerning mobility) and the Visual Analog Scale (VAS). SES was primarily assessed by educational level; age, sex and family status were included as potential confounders. Six chronic diseases were selected, each having a prevalence of at least 1% (e.g. diabetes mellitus). Multivariate analyses were conducted by logistic and linear regression.ResultsAmong adults with a chronic disease, most ‘moderate or severe problems’ are reported more often in the low (compared with the high) educational group. The same social differences are seen for VAS values, also in subgroups characterized by ‘moderate or severe problems’. Gender-specific analyses show that for women the associations with VAS values can just be seen in the total sample. For men, however, they are also present in subgroups defined by ‘moderate or severe problems’ or by the presence of a chronic disease; some of these differences exceed 10 points on the VAS scale.ConclusionsLow SES groups seem to be faced with a double burden: first, increased levels of health impairments and, second, lower levels of valuated HRQL once health is impaired. These associations should be analysed and discussed in their own right, based on interdisciplinary co-operation. Social epidemiologists could include measures of HRQL in their studies more often, for example, and health economists could consider assessing whether recommendations based on HRQL scales might include a social bias.

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The impact of disease severity on EQ-5D and SF-6D utility discrepancies in chronic heart failure

Cited by 30 publications

References 47 publications

Long-Term Association Between Frailty and Health-Related Quality of Life Among Survivors of Critical Illness

Long-Term Association Between Frailty and Health-Related Quality of Life Among Survivors of Critical Illness

Long‐term utility outcomes in patients undergoing endoscopic sinus surgery

Health-related quality of life and socioeconomic status: inequalities among adults with a chronic disease

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