The impact of diabetes on the prognostic value of left ventricular function following percutaneous coronary intervention: Insights from the British Cardiovascular Intervention Society

Abstract

DM was associated with increased 30-day mortality for all grades of LV function. The prognostic impact of DM was strongest in patients with normal LV function and less evident in patients with severe LV systolic dysfunction.

Prognostic Value of Preoperative Assessment of Left Ventricular Function in Patients Undergoing Percutaneous Coronary Intervention

“…Participants in 6 studies [ 13 , 14 , 30 , 31 , 32 , 33 ] were exclusively patients with STEMI, in 3 studies [ 34 , 35 , 36 ] participants were exclusively patients with CTO, and 3 studies [ 31 , 37 , 38 ] were patients with baseline heart failure. Thirteen studies [ 11 , 30 , 31 , 32 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 ] reported the prognostic outcomes during hospitalization, 14 studies [ 14 , 33 , 34 , 35 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 ] reported the prognostic outcomes for greater than or equal to one year, and 6 studies [ 10 , 13 , 36 , 56 , 57 , 58 ] reported the prognostic outcomes in both short and long term. The characteristics of the included studies are detailed (Table 1 , Ref.…”

“…The characteristics of the included studies are detailed (Table 1 , Ref. [ 10 , 11 , 13 , 14 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 ]). The average NOS score of all included studies was 7.6 points, with 2 studies having a minimum score of 5 [ 32 , 34 ] and 3 studies having score of 6 [ 30 , 40 , 43 ] ( Supplementary Table 1 ).…”

“…A total of 969,868 participants in 33 studies [ 10 , 11 , 13 , 14 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 ] at different stratification of baseline LVEF were included in this study and their PCI outcomes were stratified for analysis. This study found that lower baseline LVEF was associated with higher risk of all-cause mortality after PCI.…”

Use of sodium–glucose co‐transporter‐2 inhibitors in patients with and without type 2 diabetes: implications for incident and prevalent heart failure

“…Among patients with asymptomatic LV dysfunction, which may be detected in as many as two‐thirds of patients with T2D, T2D is associated with a 30% increase in the risk of incident HF compared with patients without T2D . In patients with prevalent HF, T2D was associated with an increased risk of mortality . Among 151 738 patients with T2D aged ≥65 years, the mortality rate was 32.7 per 100 patient‐years in patients with HF and was 3.7 per 100 patient‐years in patients without HF .…”

“…24,25 In patients with prevalent HF, T2D was associated with an increased risk of mortality. 26,27 Among 151 738 patients with T2D aged ≥65 years, the mortality rate was 32.7 per 100 patient-years in patients with HF and was 3.7 per 100 patient-years in patients without HF. 28 In 35 163 patients with HF, all-cause mortality rates were increased among those with T2D, regardless of aetiology.…”