the management of diabetic patients after resection of large intestinal sections is a significant clinical problem, particularly when parenteral nutrition is required, which increases the risk of hyperglycaemia. On the example of a patient who underwent subtotal resection of the small intestine due to mesenteric artery embolism, possible approaches to blood glucose lowering treatment in such patients in the perioperative period were discussed. We presented the current perspective on insulin therapy during parenteral nutrition and proposed a regimen for such treatment. Potential use of glucagon-like peptide 2 analogues in patients with short bowel syndrome was also highlighted. (clin Diabetol 2021; 10)