The impact of CyberKnife's prescription isodose percentage on intracranial target planning

Lee, Sung‐Woo; Jang, Sung Jun; Pyakuryal, Anil; Chang, Kenneth; Sio, Terence T.

doi:10.1120/jacmp.v15i5.5081

Cited by 8 publications

(6 citation statements)

References 8 publications

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“…9(a). The trade-off of increased target inhomogeneity in PTVs to reduce gradients is well-known, 17,18 and this was apparent in these results as well. The cost of the improved gradients and brain V 10Gy manifested in the maximum dose to target (PTV D 0.01cm 3) increasing from 110% to 118% and PTV D 5% − D 95% increasing from 7% to 15%.…”

Section: D Plan Quality Evaluation and Replanssupporting

confidence: 52%

Knowledge‐based prediction of plan quality metrics in intracranial stereotactic radiosurgery

et al. 2015

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The results demonstrate the ability to predict SRS QMs precisely and to identify suboptimal plans. Furthermore, the knowledge-based DVH predictions were directly used as target optimization objectives and allowed a standardized planning process that bettered the clinically approved plans. Full clinical application of this methodology can improve consistency of SRS plan quality in a wide range of PTV volume and proximity to OARs and facilitate automated treatment planning for this critical treatment site.

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Section: D Plan Quality Evaluation and Replanssupporting

confidence: 52%

Knowledge‐based prediction of plan quality metrics in intracranial stereotactic radiosurgery

et al. 2015

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“…compared dosimetric metrics of GK plans with 40%–50% IDLs and CK plans with 77%–92% IDLs. Shortly after the publication, in a letter to the editor of the journal, the coauthors of the study hypothesized that dropping the IDL could potentially improve the dose fall‐off in CK plans …”

Section: Introductionmentioning

confidence: 99%

The dosimetric impact of the prescription isodose line (IDL) on the quality of robotic stereotactic radiosurgery (SRS) plans

Xu¹,

Fan

Grimm

et al. 2017

Medical Physics

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“…Statistically, no difference was found between the applied isodoses. In clinical practice, prescription is generally assigned to the isodose lines of 50%-90% depending on the clinical protocols, target, critical organs and planning characteristics and no clear consensus exists (Lee et al 2014, Zhang et al 2014. The maximum doses are directly related with the prescription isodose levels and our study did not show any maximum dose differences within the intracranial target planning.…”

Section: Discussionmentioning

confidence: 50%

Dose analysis of InCise 2 multi leaf collimator and IRIS-based stereotactic radiotherapy plans for brain and liver tumors

Ermiş¹,

Blatti-Moreno²,

Leiser³

et al. 2019

Biomed. Phys. Eng. Express

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Second-generation multi leaf collimator (MLC) has been introduced for the CyberKnife Robotic Radiosurgery System (Accuray Inc., Sunnyvale, USA) in 2016. The aim of the present study was to compare the plan quality between InCise 2 MLC and IRIS by analyzing dose parameters for small and large targets such as brain metastases and liver tumors, respectively. Ten brain metastases targets and 10 liver targets were selected. The following parameters were analyzed: coverage, dose distributions in planning target volume (PTV) and organs at risk (OAR), conformity index (CI), Nakamura CI (nCI), homogeneity index (HI), gradient index (GI), V12 Gy within brain, treatment time, number of beams, nodes and monitor units (MU). For brain patient group, CI and nCI were lower with IRIS plans (1.18 versus 1.26; p=0.048 and 1.19 versus 1.28; p=0.033, respectively), whereas GI values were higher in InCise 2 MLC plans (0.36 versus 0.33; p<0.01). PTV mean doses were higher with IRIS plans (1.13 versus 1.16; p=0.03). For liver tumors, InCise 2 MLC plans reached higher GI values (0.32 versus 0.29; p<0.01). PTV minimum and mean doses were higher with IRIS plans (0.85 versus 0.93; p<0.01 and 1.17 versus 1.2; p=0.046, respectively). OAR's mean dose for bowel, left-right kidney and healthy liver tissue were lower with MLC plans (0.02 versus 0.04, 0.02 versus 0.05, 0.07 versus 0.10, and 0.20 versus 0.21; p<0.01, respectively). Shorter delivery time was reached with InCise 2 MLC for both groups (38 versus 56 min, and 42 versus 56 min; p<0.01, for brain and liver, respectively). Results of this study showed that second generation MLC plans for intracranial and liver targets were dosimetrically feasible. The main advantages of InCise 2 MLC are the improved dose gradient and delivery time. RECEIVED

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The impact of CyberKnife's prescription isodose percentage on intracranial target planning

Cited by 8 publications

References 8 publications

Knowledge‐based prediction of plan quality metrics in intracranial stereotactic radiosurgery

Knowledge‐based prediction of plan quality metrics in intracranial stereotactic radiosurgery

The dosimetric impact of the prescription isodose line (IDL) on the quality of robotic stereotactic radiosurgery (SRS) plans

Dose analysis of InCise 2 multi leaf collimator and IRIS-based stereotactic radiotherapy plans for brain and liver tumors

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