The impact of COVID‐19 lockdown measures on symptoms control in children with asthma: A systematic review and meta‐analysis of observational cohort studies

Kouis, Panayiotis; Lemonaris, Marios; Xenophontos, Eleana; Panayiotou, Andrie; Yiallouros, Panayiotis K.

doi:10.1002/ppul.26646

Cited by 5 publications

(1 citation statement)

References 67 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, the higher the RSV infection severity, the stronger the link. Our parent‐reported data on the link between RSV infection and wheezing is in line with previously published data from the structured research context 19–23 . A retrospective study on >68,000 children reported a higher risk of wheezing/asthma in RSV hospitalized infants compared to controls 13 .…”

Section: Discussionsupporting

confidence: 89%

Parent's perception of respiratory syncytial virus and subsequent wheezing burden: A multi‐country cross‐sectional survey

Custovic,

Mestre‐Ferrandiz,

Kragten‐Tabatabaie

et al. 2024

Pediatric Allergy Immunology

View full text Add to dashboard Cite

BackgroundRespiratory Syncytial Virus (RSV) is the leading cause of hospitalization in infants. RSV bronchiolitis is associated with an increased risk of subsequent wheezing. We aimed to document the parents' perception of the link between RSV infection and subsequent wheezing, wheezing‐related healthcare and family resources use, and its impact on family daily life.MethodsThis cross‐sectional online survey enrolled 1200 parents with at least one child ≤6y living in the United States, United Kingdom, Spain, and Italy. Children diagnosed with RSV bronchiolitis before age of 2 years were included in the RSV group, and those never diagnosed with RSV bronchiolitis in the Reference group.ResultsThe odds of wheezing were 4.5‐fold (95%CI 3.5–5.9) higher in the RSV than in the Reference group. The odds increased to 7.7‐fold (95%CI 5.4–11.1) among children who were hospitalized, and 9‐fold (95%CI 5.1–16.6) among those admitted to pediatric intensive care with RSV bronchiolitis. Similar trends were observed across all countries. In total, 57% of parents reported their child's wheezing to have moderate to severe impact on their emotional well‐being, and 53% on their daily life activities and/or social life. 64% of parents reported moderate–severe impact of wheezing on child's quality of sleep and 49% and 46% reported a moderate–severe impact on their children's emotional well‐being and physical activities.ConclusionsThis survey suggests an association between RSV infection and subsequent wheezing in children across different countries. Wheezing, especially in association with RSV infection, was associated with increased healthcare utilization and costs, and significantly impacted parents' and children daily life.

show abstract

Section: Discussionsupporting

confidence: 89%

Parent's perception of respiratory syncytial virus and subsequent wheezing burden: A multi‐country cross‐sectional survey

Custovic,

Mestre‐Ferrandiz,

Kragten‐Tabatabaie

et al. 2024

Pediatric Allergy Immunology

View full text Add to dashboard Cite

show abstract

Patterns and trends in asthma incidence rates in main Asian and Western countries and their prediction to 2030

Zheng,

Lan,

et al. 2024

Chinese Medical Journal Pulmonary and Critical Care Medicine

View full text Add to dashboard Cite

Benefits of Aeroallergen Testing on Oral Corticosteroid Bursts in Adults with Asthma

Gleeson,

Morales,

Buckey

et al. 2024

Preprint

View full text Add to dashboard Cite

BACKGROUND: Aeroallergen testing can improve precision care for persistent asthma and is recommended by the U.S. clinical guidelines. How testing benefits diverse populations of adults with asthma, and the importance of the testing modality used, are not fully understood. OBJECTIVE: We sought to evaluate whether receipt of aeroallergen testing was associated with a reduction in oral corticosteroid (OCS) bursts. METHODS: We used electronic health record data to conduct a retrospective, observational cohort study of adults with asthma who were prescribed an inhaled corticosteroid and had an Allergy/Immunology visit in a large health system between 1/1/2017-6/30/2022. Negative binomial regression models were used to evaluate whether OCS bursts in the 12-month period after an initial visit were reduced for patients who received aeroallergen testing. We also measured differences in benefit after excluding patients with chronic obstructive pulmonary disease (COPD) and smoking histories, and whether testing receipt was via skin prick or serum. RESULTS: 668/1,383 (48.3%) patients received testing. Receipt of testing was not associated with fewer bursts in all patients (incidence rate ratio (IRR)=0.83 versus no testing, p=0.059), but it was among never smokers without COPD (417/844 tested, IRR=0.68, p=0.004). The receipt of skin testing was associated with fewer bursts in all patients (418/1,383 tested, IRR=0.77, p=0.02) and among never smokers without COPD (283/844 tested, IRR=0.59 versus no testing, p=0.001). CONCLUSION: Guideline-concordant aeroallergen testing in the context of Allergy/Immunology care was associated with clinical benefit in a real-life, diverse cohort of adults with asthma. This benefit varied according to patient comorbidities and the testing modality.

show abstract

The impact of COVID‐19 lockdown measures on symptoms control in children with asthma: A systematic review and meta‐analysis of observational cohort studies

Cited by 5 publications

References 67 publications

Parent's perception of respiratory syncytial virus and subsequent wheezing burden: A multi‐country cross‐sectional survey

Parent's perception of respiratory syncytial virus and subsequent wheezing burden: A multi‐country cross‐sectional survey

Patterns and trends in asthma incidence rates in main Asian and Western countries and their prediction to 2030

Benefits of Aeroallergen Testing on Oral Corticosteroid Bursts in Adults with Asthma

Contact Info

Product

Resources

About