The Impact of Congenital Heart Diseases on Growth Parameters in Children and Their Correlations with Leptin Levels

Abstract

Children with congenital heart disease (CHD) prone to stunted growth by different parameters including weight, height and head circumference compared to a control groups, to accomplish such aim (110) children aged ranged (20 days -13 years with CHD) have enrolled in this study, (83) patients with a cyanotic CHD (75.45%) and ( 27) cyanotic type (24.54%) were compared with (171) healthy controls of similar age and sex groups. This study was done in Al-Hilla teaching hospital during the period November 1, 2017 to October 11, 2018. The results indicate a significant (2.06) retardation in all parameters in patients with CHD related to control and there is a significant retardation in weight (z = 3.06) in children with cyanotic CHD related to a cyanotic type. Also there is a significant retardation (z = 1.01) in height gain in children with cyanotic related to a cyanotic type and finally there is a significant (z = 2.09) decrease in head circumference in children with cyanotic CHD related to a cyanotic type. Serum leptin levels were also lowered in all patients with CHD. The results concluded that children with (CHD) experience early and continues decrement of all growth parameter during their life.