The impact of body mass index on maternal and neonatal outcomes: a retrospective study in a UK obstetric population, 2004–2011

Abstract

Objective To assess the prevalence of overweight and obesity, and the impact of body mass index (BMI) on maternal and neonatal outcomes, in a UK obstetric population. ). Maternal and neonatal outcomes were examined using logistic regression, adjusted for confounding variables.Main outcome measures Maternal and neonatal outcomes.Results Compared with women of normal weight, women who were overweight or obese class I were at significantly increased risk of hypertensive disorders of pregnancy (OR 1.9, 99% CI 1.7-2.3; OR 3.5, 99% CI 2.9-4.2); gestational diabetes mellitus (OR 1.7, 99% CI 1.3-2.3; OR 3.7, 99% CI 2.8-5.0); induction of labour (OR 1.2, 99% CI 1.1-1.3; OR 1.3, 99% CI 1.2-1.5); caesarean section (OR 1.4, 99% CI 1.3-1.5; OR 1.8, 99% CI 1.6-2.0); postpartum haemorrhage (OR 1.4, 99% CI 1.3-1.5; OR 1.8, 1.6-2.0); and macrosomia (OR 1.5, 99% CI 1.3-1.6; OR 1.9, 99% CI 1.6-2.2), with the risks increasing for obese classes II and III. Women in obese class III were at increased risk of preterm delivery (OR 1.6, 99% CI 1.1-2.5), stillbirth (OR 3.0, 99% CI 1.0-9.3), postnatal stay > 5 days (OR 2.1, 99% CI 1.5-3.1), and infant requiring admission to a neonatal unit (OR 1.6, 99% CI 1.0-2.6).Conclusions By categorising women into overweight and obesity subclassifications (classes I -III), this study clearly demonstrates an increasing risk of adverse outcomes across BMI categories, with women who are overweight also at significant risk.

Study of correlation between maternal body mass index with maternal and perinatal outcome

“…Similar association was reported by Deepika et al, Jain P et al and Sebire NJ et al 4,5,7 In the current study low APGAR at birth was seen more in obese group (24%) and also in underweight group (17.3%) which is in accordance with Jain P et al and Pillai S et al studies. 5,8 In the present study series perinatal deaths were more in obese (12%) and overweight group (10%) followed by underweight group (9.3%), which correlates with the study conducted by Jain P et al 5 …”

Predicting Nonhemolytic Neonatal Hyperbilirubinemia

“…12 Therefore, current best available knowledge is limited by imprecise estimates of size and direction of significant risk factors. In addition, recommendations based on older data may not take recent changes in the reproductive epidemiology landscape, mainly increased maternal age, 23 BMI, 24 and rates of operative deliveries, 25 into account. Finally, there is no previous study with sufficient power to disentangle interactions between different risk factors, which is necessary for individualized risk prediction.…”

Postpartum Haemorrhage; Frequency in Obese Primigravid Women

“…6,7 Maternal obesity is associated with an elevated risk 2 of intrapartum caesarean section, predominantly for failure to progress, the mechanism of which is suggested to be due to reduced uterine contractility. 8,9 In a former published literature concerning the effect of maternal obesity on mode of delivery after induction of labor for prolonged pregnancy, there was no significant trend for increasing postpartum hemorrhage with increasing maternal BMI. 10 An increased trend in the incidence of postpartum hemorrhage over time has been observed in high resource countries, but the reason for this increase remains uncertain.…”