The impact of birth weight on the level of lung function and lung function decline in the general adult population. The Inter99 study

Baumann, Sophie; Godtfredsen, Nina; Lange, Peter; Pisinger, Charlotta

doi:10.1016/j.rmed.2015.08.011

Cited by 19 publications

(11 citation statements)

References 37 publications

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“…Baumann et al, 33 who studied more than 4000 adults divided into 4 subgroups based on their birth weight (<2500 g, 2500–3000 g, 3000–3500 g, >3500 g), found that the lower the birth weight, the lower the mean FEV 1 %pred ( p < 0.001) and FVC%pred ( p < 0.002), but did not find any statistical differences in FEV 1 /FVC%pred. A second spirometric examination carried out 5 years later did not find significant differences in terms of FEV 1 or FVC, but found a statistically significant reduction in FEV 1 /FVC ( p < 0.01) as compared with the first examination and noted a correlation between FEV 1 /FVC and birth weight.…”

Section: Discussionmentioning

confidence: 98%

“…A large percentage of individuals do not have well-kept medical records from their birth or early childhood, which can have an impact on research results. 33 Another major problem in evaluating the consequences of preterm birth lies in attempting to account for the large number of post-birth factors; the most important of the many such factors mentioned in the literature include: duration of hospitalization after birth, respiratory symptoms experienced, the need for mechanical ventilation or oxygen therapy, and the mother’s pre- and post-partum smoking habits. 18 At present, increasing attention is also being paid to various factors present in adulthood which may likewise affect the current status of the respiratory system, and controlling for these could make research results into the impact of preterm birth significantly more reliable – these include respiratory infections experienced in childhood and adulthood, especially chronic cough or diagnosed asthma, active or passive cigarette smoking, diet, physical activity, and alcohol consumption.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Are preterm-born survivors at risk of long-term respiratory disease?

Kaczmarczyk

Wiszomirska

Szturmowicz

et al. 2017

Ther Adv Respir Dis

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Background:To evaluate the long-term impact of preterm birth on respiratory function in female patients born preterm, we undertook spirometric examinations twice, as they reached the age of puberty, then follow-up examinations of part of the same cohort in adulthood. We sought evidence that preterm birth is correlated with poorer spirometric results into adulthood.Methods:A total of 70 girls (aged 12.2 ± 1.5 years in 1997) who had been born preterm (at 34.7 ± 1.86 weeks, none having experienced bronchopulmonary dysplasia) took part in spriometric examinations in 1997 and again in 1998. Of those, after a gap of 17 years, a group of 12 were successfully recontacted and participated in the 2015 examination as adults (then aged 27.6 ± 2.6 years, born at 34.5 ± 1.92 weeks). We compared spirometric results across the adolescent and adult examinations, and compared the adult results with an adult reference group.Results:The percentage values of FEV1 (forced expiratory volume in 1 s), FVC (forced vital capacity) and MVV (maximal voluntary ventilation) showed significant improvement between the two examinations in the early adolescent period. In adulthood, FEV1%pred (percentage predicted forced expiratory volume in 1 s) showed no statistically significant difference. The mean values of both FVC and FVC%pred (percentage predicted forced vital capacity) for the preterm-born group were lower than for the reference group, but this was not statistically significant. The preterm-born group showed lower values of such parameters as forced expiratory flow at 25–75% of FVC, MEF25 (maximal expiratory flow at 25% of forced vital capacity) and FEV1/FVC as compared with the reference group, but again without statistical significance.Conclusions:(1) A somewhat below-norm level of respiratory parameters among preterm-born girls entering pubescence may attest to continued negative impact on their respiratory system.(2) A significant improvement in their spirometric results 1 year later may indicate that pubescence helps compensate for the earlier negative effect of preterm birth.(3) No significant differences were seen in lung function in preterm-born adults as compared with a reference group of adults, although the preterm-born group did exhibit lower values of all parameters studied and more frequent obstructive disorders.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Are preterm-born survivors at risk of long-term respiratory disease?

Kaczmarczyk

Wiszomirska

Szturmowicz

et al. 2017

Ther Adv Respir Dis

View full text Add to dashboard Cite

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“…As the pulmonary parenchyma grows, there may be a progressive improvement in parameters related to pulmonary volume due to alveolar multiplication. However, alterations in pulmonary flow may persist until adolescence or adulthood [4,5].…”

Section: Introductionmentioning

confidence: 99%

Pulmonary function in former very low birth weight preterm infants in the first year of life

Gonçalves

Wandalsen

Scavacini

et al. 2018

Respiratory Medicine

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“…Low birth weight is a well‐established risk factor for cardiovascular disease,1 type 2 diabetes mellitus,2 and hypertension,3 as well as several other known atrial fibrillation (AF) risk factors, such as pulmonary function 4, 5. There are 3 previous studies that report on associations between self‐reported birth weight and incident AF, with divergent results.…”

Section: Introductionmentioning

confidence: 99%

Early Life Risk Factors for Incident Atrial Fibrillation in the Helsinki Birth Cohort Study

Johnson

Salonen

Kajantie

et al. 2017

JAHA

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BackgroundEarly life risk factors are associated with cardiometabolic disease, but have not been fully studied in atrial fibrillation (AF). There are discordant results from existing studies of birth weight and AF, and the impact of maternal body size, gestational age, placental size, and birth length is unknown.Methods and ResultsThe Helsinki Birth Cohort Study includes 13 345 people born as singletons in Helsinki in the years 1934–1944. Follow‐up was through national registries, and ended on December 31, 2013, with 907 incident cases. Cox regression analyses stratified on year of birth were constructed for perinatal variables and incident AF, adjusting for offspring sex, gestational age, and socioeconomic status at birth. There was a significant U‐shaped association between birth weight and AF (P for quadratic term=0.01). The lowest risk of AF was found among those with a birth weight of 3.4 kg (3.8 kg for women [85th percentile] and 3.0 kg for men [17th percentile]). High maternal body mass index (≥30 kg/m2) predicted offspring AF; hazard ratio 1.36 (95% CI 1.07–1.74, P=0.01) compared with normal body mass index (<25 kg/m2). Maternal height was associated with early‐onset AF (<65.3 years), hazard ratio 1.47 (95% CI 1.24–1.74, P<0.0001), but not with later onset AF. Results were independent of incident coronary artery disease, hypertension, or diabetes mellitus.ConclusionsHigh maternal body mass index during pregnancy and maternal height are previously undescribed predictors of offspring AF. Efforts to prevent maternal obesity might reduce later AF in offspring. Birth weight has a U‐shaped relation to incident AF independent of other perinatal variables.

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The impact of birth weight on the level of lung function and lung function decline in the general adult population. The Inter99 study

Cited by 19 publications

References 37 publications

Are preterm-born survivors at risk of long-term respiratory disease?

Are preterm-born survivors at risk of long-term respiratory disease?

Pulmonary function in former very low birth weight preterm infants in the first year of life

Early Life Risk Factors for Incident Atrial Fibrillation in the Helsinki Birth Cohort Study

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