2009
DOI: 10.1111/j.1751-7133.2008.00030.x
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The Impact of Anemia on the Prognosis of Chronic Heart Failure: A Meta‐Analysis and Systemic Review

Abstract: The aim of this study was to assess the impact of anemia on the clinical outcomes of chronic heart failure (CHF) by a meta‐analysis and systemic review of published literatures. Twenty published English‐language articles were selected from Medline, PubMed, and ISI Database. Clinical data were extracted, pooled, and analyzed with a fixed‐ or random‐effects model. A total of 97,699 patients with CHF were identified from the published studies. Meta‐analysis of these studies indicated that anemia is associated wit… Show more

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Cited by 51 publications
(36 citation statements)
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“…For example, a particularly strong adverse relationship is seen between anemia and outcomes in heart failure. 9,10 Little is known regarding the relationship of hemoglobin or change in anemia status over time and cardiovascular events and mortality in stable coronary artery disease. The aims of the current analysis from the large contemporary global CLARIFY (ProspeCtive observational LongitudinAl RegIstry oF patients with stable coronary arterY disease) registry were to assess the relationship between hemoglobin, or change in anemia status over time, and 4-year mortality and cardiovascular and major bleeding events.…”
Section: Introductionmentioning
confidence: 99%
“…For example, a particularly strong adverse relationship is seen between anemia and outcomes in heart failure. 9,10 Little is known regarding the relationship of hemoglobin or change in anemia status over time and cardiovascular events and mortality in stable coronary artery disease. The aims of the current analysis from the large contemporary global CLARIFY (ProspeCtive observational LongitudinAl RegIstry oF patients with stable coronary arterY disease) registry were to assess the relationship between hemoglobin, or change in anemia status over time, and 4-year mortality and cardiovascular and major bleeding events.…”
Section: Introductionmentioning
confidence: 99%
“…Moreover, these patients had worse exercise tolerance (NYHA III-IV) and lower ejection fraction of the left ventricle (LVOT) [3].…”
Section: Discussionmentioning
confidence: 99%
“…Results of the latest researches proved that the basis of the ACD is an immune-mediated mechanism: imbalance of cytokine and reticuloendothelial system cell interaction causes disorders of iron homeostasis, proliferation of erythropoiesis precursors, erythropoietin production, and life time of erythrocytes [2,7,8]. Discovery of hepcidin -an acute-phase iron-regulating protein had a revolutionary signifi cance that proved connection between an immune mechanism of iron metabolism disorders and progress of the ACD [3,7,9].…”
Section: Cardiovascular Pathology and Aneamiamentioning
confidence: 99%
“…Захидова К. Х., Кулиев Ф. А. бликованных в 2009 году, доказали достоверную ассо-циацию анемии с высоким риском смертельного исхода при СН, при этом данные пациенты имели худшую толерантность к нагрузкам (III-IV ФК) и низкую фракцию выброса (ФВ) левого желудочка (ЛЖ) [3]. С одной стороны, клиницисты акцентиро-вали свое внимание на роли эритропоэтина (ЭПО), его дисфункции, т. к. развитие анемии у пациентов с ХСН может быть с низким или повышенным ЭПО [4].…”
Section: метоксиполиэтиленгликоль-эпоэтина-бета в лечении Aнемии при unclassified