The impact of age structure and vaccine prioritization on COVID-19 in West Africa

Taboe, Hémaho B.; Asare-Baah, Michael; Yesmin, Afsana; Ngonghala, Calistus N.

doi:10.1016/j.idm.2022.08.006

Cited by 11 publications

(11 citation statements)

References 50 publications

(53 reference statements)

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“… Explicitly including the impact of voluntary testing to detect infected individuals who do not have clinical symptoms of the disease. Although this was not done in [47] , [48] , [49] , [50] , [51] , [52] , [53] , [54] , [55] , [56] , detection has been incorporated in some models for COVID-19 dynamics (e.g., [57] , [58] , [59] ). Specifically, the epidemic (SIDARTHE) model developed in [57] consists of eight epidemiological compartments of Susceptible (

), Infected (

), Diagnosed (

), Ailing (

), Recognized (

), threatened (

), Healed (

) and Extinct (

) individuals, where (in the formulation/notation in [57] ) individuals in the

and

compartments are undetected while those in the

, and

are detected.…”

Section: Methodsmentioning

confidence: 99%

Unraveling the dynamics of the Omicron and Delta variants of the 2019 coronavirus in the presence of vaccination, mask usage, and antiviral treatment

Ngonghala

Taboe²,

Safdar³

et al. 2023

Applied Mathematical Modelling

View full text Add to dashboard Cite

), Infected (

), Diagnosed (

), Ailing (

), Recognized (

), threatened (

), Healed (

) and Extinct (

) individuals, where (in the formulation/notation in [57] ) individuals in the

and

compartments are undetected while those in the

, and

are detected.…”

Section: Methodsmentioning

confidence: 99%

Unraveling the dynamics of the Omicron and Delta variants of the 2019 coronavirus in the presence of vaccination, mask usage, and antiviral treatment

Ngonghala

Taboe²,

Safdar³

et al. 2023

Applied Mathematical Modelling

View full text Add to dashboard Cite

“…The SEIR-type compartment models and the models alike were usually governed to investigate the epidemiological characteristics and dynamic behaviors of infectious diseases. The recent studies combining the multi-age groups and the hospitalization data in ( Kimathi et al., 2021 ; Lu et al., 2019 ; Zhou et al., 2019 ; Li et al., 2022 ; Makhoul et al., 2021 ; Liu & Wei, 2022 ; Wei & Xue, 2020 ; Yu et al., 2023 ; Zhang & Wei, 2020 ; Wei et al., 2021 ; Zhai et al., 2023 ; Taboe et al., 2022 ; Wei et al., 2023 ; Wu & Feng, 2024 ), were less. For instance, the studies for two-age groups compartment model in ( Taboe et al., 2022 ) indicated that the individuals under 65 years old were the primary drivers of the COVID-19 pandemic in West Africa.…”

Section: Introductionmentioning

confidence: 99%

An SEIHR model with age group and social contact for analysis of Fuzhou COVID-19 large wave

Lan,

Chen,

Zhou

et al. 2024

Infectious Disease Modelling

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“…Even though various research studies are being conducted in Africa, they largely focus on COVID-19 vaccination prioritization strategies [29][30][31] or vaccine acceptance [32][33][34].…”

Section: Introductionmentioning

confidence: 99%

Assessing the Impact of Vaccination on the Dynamics of COVID-19 in Africa: A Mathematical Modeling Study

et al. 2023

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Several effective COVID-19 vaccines are administered to combat the COVID-19 pandemic globally. In most African countries, there is a comparatively limited deployment of vaccination programs. In this work, we develop a mathematical compartmental model to assess the impact of vaccination programs on curtailing the burden of COVID-19 in eight African countries considering SARS-CoV-2 cumulative case data for each country for the third wave of the COVID-19 pandemic. The model stratifies the total population into two subgroups based on individual vaccination status. We use the detection and death rates ratios between vaccinated and unvaccinated individuals to quantify the vaccine’s effectiveness in reducing new COVID-19 infections and death, respectively. Additionally, we perform a numerical sensitivity analysis to assess the combined impact of vaccination and reduction in the SARS-CoV-2 transmission due to control measures on the control reproduction number (Rc). Our results reveal that on average, at least 60% of the population in each considered African country should be vaccinated to curtail the pandemic (lower the Rc below one). Moreover, lower values of Rc are possible even when there is a low (10%) or moderate (30%) reduction in the SARS-CoV-2 transmission rate due to NPIs. Combining vaccination programs with various levels of reduction in the transmission rate due to NPI aids in curtailing the pandemic. Additionally, this study shows that vaccination significantly reduces the severity of the disease and death rates despite low efficacy against COVID-19 infections. The African governments need to design vaccination strategies that increase vaccine uptake, such as an incentive-based approach.

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The impact of age structure and vaccine prioritization on COVID-19 in West Africa

Cited by 11 publications

References 50 publications

Unraveling the dynamics of the Omicron and Delta variants of the 2019 coronavirus in the presence of vaccination, mask usage, and antiviral treatment

Unraveling the dynamics of the Omicron and Delta variants of the 2019 coronavirus in the presence of vaccination, mask usage, and antiviral treatment

An SEIHR model with age group and social contact for analysis of Fuzhou COVID-19 large wave

Assessing the Impact of Vaccination on the Dynamics of COVID-19 in Africa: A Mathematical Modeling Study

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