The impact of a computerized physician order entry system on medical errors with antineoplastic drugs 5 years after its implementation

Cuervo, M. Sánchez; Sanchís, AM Rojo; López, Carlos Rosales; Silanes, E. de Salazar López de Gómez; Gramage, T; Vicedo, T. Bermejo

doi:10.1111/jcpt.12305

Cited by 9 publications

(8 citation statements)

References 20 publications

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“…The different types of CPOE used in the studies are listed in Table 2 . One of the studies reported complete elimination of all CMEs with adequate training and acclimatisation of personnel over a period of 5 years [ 33 ]. Two studies did not provide inferential statistics; however, the number of events pre- and post-CPOE differed significantly (Table 2 , P <0.05) [ 28 , 34 ].…”

Section: Resultsmentioning

confidence: 99%

“…All 11 studies were published between 2006 and 2018 and had a single-arm design in which the CPOE pre-and post-implementation phases were compared [26][27][28][29][30][31][32][33][34][35][36]. Among these, five studies were from the USA, three from Europe, and three from Asian countries.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Three studies were prospectively designed to collect data from the prescription validation process while implementing CPOE [28,33,34], while in five studies, the data were collected as part of the routine quality assurance process and analysed retrospectively [26,[29][30][31][32]. The data collection methods were not clearly explained in three studies [27,35,36].…”

Section: Study Characteristicsmentioning

confidence: 99%

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Impact of computerised physician order entry (CPOE) on the incidence of chemotherapy-related medication errors: a systematic review

Srinivasamurthy

Ashokkumar

Kodidela

et al. 2021

Eur J Clin Pharmacol

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Purpose Computerised prescriber (or physician) order entry (CPOE) implementation is one of the strategies to reduce medication errors. The extent to which CPOE influences the incidence of chemotherapy-related medication errors (CMEs) was not previously collated and systematically reviewed. Hence, this study was designed to collect, collate, and systematically review studies to evaluate the effect of CPOE on the incidence of CMEs. Methods A search was performed of four databases from 1 January 1995 until 1 August 2019. English-language studies evaluating the effect of CPOE on CMEs were selected as per inclusion and exclusion criteria. The total CMEs normalised to total prescriptions pre- and post-CPOE were extracted and collated to perform a meta-analysis using the ‘meta’ package in R. The systematic review was registered with PROSPERO CRD42018104220. Results The database search identified 1621 studies. After screening, 19 studies were selected for full-text review, of which 11 studies fulfilled the selection criteria. The meta-analysis of eight studies with a random effects model showed a risk ratio of 0.19 (95% confidence interval: 0.08–0.44) favouring CPOE (I2 = 99%). Conclusion The studies have shown consistent reduction in CMEs after CPOE implementation, except one study that showed an increase in CMEs. The random effects model in the meta-analysis of eight studies showed that CPOE implementation reduced CMEs by 81%.

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Section: Resultsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

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Impact of computerised physician order entry (CPOE) on the incidence of chemotherapy-related medication errors: a systematic review

Srinivasamurthy

Ashokkumar

Kodidela

et al. 2021

Eur J Clin Pharmacol

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“…In this regard, Sanchez Cuervo et al indicated that although CPOE could reduce MEs, it may lead to new types of errors, especially in its first implementation. Moreover, they indicated that no new types of MEs were observed once physicians had become accustomed to using the system ( 20 ). In addition, Wu et al stated that several factors had an important role on the efficacy of CPOE such as urgent situations, thus, urgency played a more important role in CPOE numeric typing error-making than typing skills and habits.…”

Section: Discussionmentioning

confidence: 99%

The impact of computerized physician order entry on prescription orders: A quasi-experimental study in Iran

Khammarnia

Sharifian

Zand

et al. 2017

Med. J. Islam. Republic Iran

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Background: One way to reduce medical errors associated with physician orders is computerized physician order entry (CPOE) software. This study was conducted to compare prescription orders between 2 groups before and after CPOE implementation in a hospital. Methods: We conducted a before-after prospective study in 2 intensive care unit (ICU) wards (as intervention and control wards) in the largest tertiary public hospital in South of Iran during 2014 and 2016. All prescription orders were validated by a clinical pharmacist and an ICU physician. The rates of ordering the errors in medical orders were compared before (manual ordering) and after implementation of the CPOE. A standard checklist was used for data collection. For the data analysis, SPSS Version 21, descriptive statistics, and analytical tests such as McNemar, chi-square, and logistic regression were used. Results: The CPOE significantly decreased 2 types of errors, illegible orders and lack of writing the drug form, in the intervention ward compared to the control ward (p< 0.05); however, the 2 errors increased due to the defect in the CPOE (p< 0.001). The use of CPOE decreased the prescription errors from 19% to 3% (p= 0.001), However, no differences were observed in the control ward (p<0.05). In addition, more errors occurred in the morning shift (p< 0.001). Conclusion: In general, the use of CPOE significantly reduced the prescription errors. Nonetheless, more caution should be exercised in the use of this system, and its deficiencies should be resolved. Furthermore, it is recommended that CPOE be used to improve the quality of delivered services in hospitals.

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“…In fact, anticancer drugs present a narrow therapeutic index with potentially lethal adverse events. Many studies have highlighted the benefit of computerised prescription (CP) in oncology 1 2. However, CP may lead to the emergence of new errors defined as e-iatrogenesis that can result in unintended consequences 3.…”

mentioning

confidence: 99%

Safety of chemotherapy prescription and production software: proposal of specific guidelines to test new versions

Pourroy

Benizri

Roubaud³

et al. 2016

Eur J Hosp Pharm

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The impact of a computerized physician order entry system on medical errors with antineoplastic drugs 5 years after its implementation

Cited by 9 publications

References 20 publications

Impact of computerised physician order entry (CPOE) on the incidence of chemotherapy-related medication errors: a systematic review

Impact of computerised physician order entry (CPOE) on the incidence of chemotherapy-related medication errors: a systematic review

The impact of computerized physician order entry on prescription orders: A quasi-experimental study in Iran

Safety of chemotherapy prescription and production software: proposal of specific guidelines to test new versions

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