“…Moreover, the ecCuZnSOD transcript in hemocytes was significantly increased by injection of b-glucan or peptidoglycan in S. serrata, suggesting that ecCuZnSOD gene expression is involved in the immune system against challenge [59]. Further, ecCuZnSOD transcripts/activities have also been described to increase under different challenge conditions using different treatments like dsRNA or lower ambient ammonia in Chinese mitten crab Eriocheir sinensis [60,61], Cd in marine crab Charybdis japonica [62], b-glucan in white shrimp Litopenaeus vannamei [63]/freshwater prawn Macrobrachium rosenbergii [64], laminarin or LPS in freshwater crayfish P. leniusculus [47], and b-1, 3-glucan or other stimuli in shrimps…”