The imaging definition of bronchiectasis in children: Is it time for a change?

Brody, Alan S.; Chang, Anne B.

doi:10.1002/ppul.23901

Cited by 6 publications

(1 citation statement)

References 14 publications

(27 reference statements)

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“…ratios should be defined and determined. When determining BAR, some clinicians prefer to use the outer airway diameter [15]. However, the ERS pediatric guidelines [13] recommend using the inner airway diameter for the BAR, but this was a conditional recommendation due to limited evidence [13].…”

Section: A Ba Pairs Bar and The Need For Automated Systemsmentioning

confidence: 99%

Methods for Detection and Measurement of Potential Broncho-Arterial Pairs in Chest Computed Tomography Scans of Children

Beeravolu,

Azam,

Jonkman

et al. 2024

IEEE Access

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Bronchiectasis, one of the most neglected chronic lung conditions, has a high individual disease burden and economic cost and causes poor quality of life in children/adolescents and adults. Advances in image quality and a dramatic reduction in acquisition times, multiple high-resolution chest tomography (HRCT) acquisitions, and reconstructions of the lung have resulted in accurate categorization and determination of the extent of lung parenchyma and airway abnormality. For bronchiectasis, the diagnosis is confirmed using the key feature of abnormally increased broncho-arterial (B.A.) ratio (BAR), with or without other abnormalities, e.g., bronchial wall thickening, lack of bronchial tapering, and mucus plugging. Most of these features require shape analysis of the airway and artery regions to perform various assessments that can have inter-rater variability and are time-consuming. This challenge is amplified in pediatric patients due to age-related anatomical variations. The anatomical differences and variations in airway structures between Infants, Early Childhood, and middle Childhood can impact how the images can be processed and analyzed. To address this, we proposed two novel image-processing methods to detect and measure the B.A. pairs. The first method uses an optimized connected component labelling (CCL) algorithm to construct bounding boxes around the objects (airway, artery) and extract the regions of interest (ROIs) for potential B.A. pairs. The second method allows us to calculate 4 or 6 diameters for each object in the ROIs and use their mean value as the final diameter, demonstrating agreement with manual readings. Evaluating against a diverse set of HRCT scans from various categories validates our proposed methods' significance and practical utility in detecting and measuring the disjointed B.A. pairs to assess increased BAR.

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Section: A Ba Pairs Bar and The Need For Automated Systemsmentioning

confidence: 99%

Methods for Detection and Measurement of Potential Broncho-Arterial Pairs in Chest Computed Tomography Scans of Children

Beeravolu,

Azam,

Jonkman

et al. 2024

IEEE Access

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Bronchiectasis: An Evidence-Based Approach to Diagnosis

Maturu

2024

Curr Pulmonol Rep

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Bronchiectasis in children: diagnosis and treatment

2018

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Bronchiectasis is conventionally defined as irreversible dilatation of the bronchial tree. Bronchiectasis unrelated to cystic fibrosis is an increasingly appreciated cause of chronic respiratory-related morbidity worldwide. Few randomised controlled trials provide high-level evidence for management strategies to treat the children affected by bronchiectasis. However, both decades-old and more recent studies using technological advances support the notion that prompt diagnosis and optimal management of paediatric bronchiectasis is particularly important in early childhood. Although considered to be of a non-reversible nature, mild bronchiectasis determined by radiography might be reversible at any age if treated early, and the lung function decline associated with disease progression could then be halted. Although some management strategies are extrapolated from cystic fibrosis or adult-based studies, or both, non-cystic fibrosis paediatric-specific data to help diagnose and manage these children still need to be generated. We present current knowledge and an updated definition of bronchiectasis, and review controversies relating to the management of children with bronchiectasis, including applying the concept of so-called treatable traits.

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The imaging definition of bronchiectasis in children: Is it time for a change?

Cited by 6 publications

References 14 publications

Methods for Detection and Measurement of Potential Broncho-Arterial Pairs in Chest Computed Tomography Scans of Children

Methods for Detection and Measurement of Potential Broncho-Arterial Pairs in Chest Computed Tomography Scans of Children

Bronchiectasis: An Evidence-Based Approach to Diagnosis

Bronchiectasis in children: diagnosis and treatment

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