Let Go be a semisimple Lie group, let Ko be a maximal compact subgroup of Go and let k ⊂ g denote the complexification of their Lie algebras. Let G be the adjoint group of g and let K be the connected Lie subgroup of G with Lie algebra ad(k). If U (g) is the universal enveloping algebra of g then U (g) K will denote the centralizer of K in U (g). Also let P : U (g) −→ U (k) ⊗ U (a) be the projection map corresponding to the direct sum U (g) = U (k) ⊗ U (a) ⊕ U (g)n associated to an Iwasawa decomposition of Go adapted to Ko. In this paper we give a characterization of the image of U (g) K under the injective antihomorphism P : U (g) K −→ U (k) M ⊗ U (a), considered by Lepowsky in [10], when Go is locally isomorphic to F4.