The ILO and Japanese Public Employee Unions

Handsaker, Morrison; Handsaker, Marjorie

doi:10.1111/j.1468-232x.1967.tb01065.x

Cited by 2 publications

(1 citation statement)

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“…The structural features were imputed into the merged imputation panel using Osprey (v0.1-9) 132,133 by running ospreyIBS followed by osprey using default parameters plus “-iter 100”, the SHAPEIT4 genetic map for GRCh38 chr6, and a target genome interval of chr6:31980500-32046500.…”

Section: Methodsmentioning

confidence: 99%

Concerted neuron-astrocyte gene expression declines in aging and schizophrenia

Ling,

Nemesh,

Goldman

et al. 2024

Preprint

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Human brains vary across people and over time; such variation is not yet understood in cellular terms. Here we describe a striking relationship between people's cortical neurons and cortical astrocytes. We used single-nucleus RNA-seq to analyze the prefrontal cortex of 191 human donors ages 22-97 years, including healthy individuals and persons with schizophrenia. Latent-factor analysis of these data revealed that in persons whose cortical neurons more strongly expressed genes for synaptic components, cortical astrocytes more strongly expressed distinct genes with synaptic functions and genes for synthesizing cholesterol, an astrocyte-supplied component of synaptic membranes. We call this relationship the Synaptic Neuron-and-Astrocyte Program (SNAP). In schizophrenia and aging -- two conditions that involve declines in cognitive flexibility and plasticity -- cells had divested from SNAP: astrocytes, glutamatergic (excitatory) neurons, and GABAergic (inhibitory) neurons all reduced SNAP expression to corresponding degrees. The distinct astrocytic and neuronal components of SNAP both involved genes in which genetic risk factors for schizophrenia were strongly concentrated. SNAP, which varies quantitatively even among healthy persons of similar age, may underlie many aspects of normal human interindividual differences and be an important point of convergence for multiple kinds of pathophysiology.

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Section: Methodsmentioning

confidence: 99%

Concerted neuron-astrocyte gene expression declines in aging and schizophrenia

Ling,

Nemesh,

Goldman

et al. 2024

Preprint

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The ILO to the Rescue? A Mote on Japanese and Australian Experiences

Easson¹

1995

Econ. labour relat. rev.

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In the aftermath of the Victorian State election in 1992, the election of a conservative administration and the enactment of new State labour laws, momentum gathered within the labour movement to utilise ILO Conventions as a means of striking down the Victorian laws. The idea was: the ILO to the rescue; that the external affairs power of the Commonwealth Constitution together with legislation based on ratified ILO Conventions might be utilised to salvage some important trade union and related rights.At different periods in the post-War histories of the Australian and Japanese labour movements, there have been calls for utilising International Labour Organisation Conventions in order to salvage some important trade union rights that those movements have fought to achieve over this century.

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The ILO and Japanese Public Employee Unions

Cited by 2 publications

References 1 publication

Concerted neuron-astrocyte gene expression declines in aging and schizophrenia

Concerted neuron-astrocyte gene expression declines in aging and schizophrenia

The ILO to the Rescue? A Mote on Japanese and Australian Experiences

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