The identification of ulcerative plaque with high resolution duplex carotid scanning.

Bluth, Edward I.; McVay, Leon V.; Merritt, Christopher R. B.; Sullivan, Michael A.

doi:10.7863/jum.1988.7.2.73

Cited by 58 publications

(14 citation statements)

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“…In our work, US-ECD sensitivity in detecting ulcers was only 37.5%; these values are similar to data produced by other authors. 24,43,44 This can be ascribed, in part, to the fact that acoustic shadowing from calcification obscures ulcers, and the sonography probe may not be parallel to the axis of the vessel in the region of the ulceration. In our radiology practice, we always looked for ulceration when we analyzed carotid arteries, and considering the high MDCTA sensitivity and specificity, a radiologist should look for plaque ulcerations.…”

Section: Discussionmentioning

confidence: 99%

CT and Ultrasound in the Study of Ulcerated Carotid Plaque Compared with Surgical Results: Potentialities and Advantages of Multidetector Row CT Angiography

Saba

Caddeo²,

Sanfilippo³

et al. 2007

American Journal of Neuroradiology

197

120

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Section: Discussionmentioning

confidence: 99%

CT and Ultrasound in the Study of Ulcerated Carotid Plaque Compared with Surgical Results: Potentialities and Advantages of Multidetector Row CT Angiography

Saba

Caddeo²,

Sanfilippo³

et al. 2007

American Journal of Neuroradiology

197

120

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“…13 Saba et al 15 have recently showed that ultrasound has a high specificity (93%) but a low sensitivity (38%) for the detection of carotid ulceration, which is in concordance with previous studies. 20,21 The low sensitivity can be ascribed, in part, to the fact that acoustic shadowing from calcifications obscures the presence of ulcerations.…”

Section: Discussionmentioning

confidence: 99%

Atherosclerotic Plaque Surface Morphology in the Carotid Bifurcation Assessed With Multidetector Computed Tomography Angiography

Weert

Cretier

Groen

et al. 2009

Stroke

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Background and Purpose-Complicated (irregular or ulcerated) carotid plaques have proven to be independent predictors of stroke. We analyzed the frequency and location of plaque irregularities in a large cohort of patients with ischemic cerebrovascular disease and the relation with severity of stenosis, cardiovascular risk factors, and symptomatology. Methods-Multidetector CT angiography images from 406 patients were evaluated. Plaque surface morphology was classified as smooth, irregular, or ulcerated. The location of the ulceration was defined as proximal or distal to the point of maximum stenosis. Results-Atherosclerotic plaques with an open lumen were present in 448 carotid arteries; these plaques were classified as: smooth, 276 (62%); irregular, 99 (22%); and ulcerated, 73 (16%). Sixty-two (69%) of the ulcerations were located proximal to the point of maximum luminal stenosis. Complicated plaques were significantly (PϽ0.001) more common in carotid arteries with stenosis Ͼ30% than in those with stenosis Ͻ30%. There is an association between complicated plaques and hypercholesterolemia (OR, 3.0) and a trend toward an association with smoking (OR, 1.9). Complicated plaques are more often present in the symptomatic carotid artery than in the contralateral asymptomatic carotid artery; however, this is fully attributed to a significantly higher degree of stenosis in the symptomatic arteries. Conclusions-Multidetector CT angiography allows the classification of atherosclerotic carotid plaque surface. Complicated plaques are frequent in atherosclerotic carotid disease, especially with higher stenosis degree. Ulcerations are mostly located in the proximal part of the atherosclerotic plaque. Hypercholesterolemia and smoking are related with the presence of complicated plaques.

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“…Using these criteria, B-mode imaging has failed to provide a satisfactory diagnostic yield for ulcerative plaques with a sensitivity of only 47% [70]. Other groups have been unable to distinguish between the presence or absence of intimal ulcerations with B-mode scans [57]. Diagnostic sensitivity for detecting plaque ulceration with ultrasound is affected by the degree of carotid stenosis and increases to 77% in plaques associated with 50% or less stenosis [27].…”

Section: Plaque Development – the Intermediate Stagementioning

confidence: 99%

Ultrasound and Arterial Wall Disease

Hennerici¹,

Baezner²,

Daffertshofer³

2003

Cerebrovasc Dis

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Rapid progress in non-invasive ultrasound techniques has resulted in a wide variety of clinical applications for the assessment of cerebrovascular diseases. Recent highlights in ultrasound research include the evaluation of vascular ageing as a degenerative process, the demonstration of plaque development, motion and vulnerability in atherosclerosis and multi-dimensional as well as innovative imaging techniques (e.g., compound imaging) to depict early and small vascular lesions. In addition, echo-contrast agents have been used to compensate for difficulties in visualising late, severe or subtotal obstructive plaques, but failed to be really superior to conventional techniques as evidenced in a prospective, multi-centre trial (Contrast Enhanced Duplex sonography versus Arteriography Studies – CEDAS). With increasing sophistication of ultrasound methodology, it becomes essential to establish standards for data acquisition and interpretation: three consensus meetings have provided detailed recommendations on quantification of carotid atherosclerosis, characterisation of carotid artery plaques and detection of microembolism by transcranial Doppler as a potential indicator of stroke risk.

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The identification of ulcerative plaque with high resolution duplex carotid scanning.

Cited by 58 publications

References 0 publications

CT and Ultrasound in the Study of Ulcerated Carotid Plaque Compared with Surgical Results: Potentialities and Advantages of Multidetector Row CT Angiography

CT and Ultrasound in the Study of Ulcerated Carotid Plaque Compared with Surgical Results: Potentialities and Advantages of Multidetector Row CT Angiography

Atherosclerotic Plaque Surface Morphology in the Carotid Bifurcation Assessed With Multidetector Computed Tomography Angiography

Ultrasound and Arterial Wall Disease

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