The identification of selenium species in biological samples

Edmonds, John S.; Morita, Masatoshi

doi:10.1002/(sici)1099-0739(200003)14:3<133::aid-aoc966>3.0.co;2-3

Cited by 21 publications

(5 citation statements)

References 128 publications

(114 reference statements)

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“…Some vegetables can grow under selenium-rich soil and accumulate selenium (onions, leeks, garlic, and broccoli) [205]. These vegetables accumulate selenium up to 50-fold or higher.…”

Section: Health Benefits Of Selenium In Humansmentioning

confidence: 99%

Selenium. Role of the Essential Metalloid in Health

Kurokawa

Berry

2013

Metal Ions in Life Sciences

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Selenium is an essential micronutrient in mammals, but is also recognized as toxic in excess. It is a non-metal with properties that are intermediate between the chalcogen elements sulfur and tellurium. Selenium exerts its biological functions through selenoproteins. Selenoproteins contain selenium in the form of the 21st amino acid, selenocysteine (Sec), which is an analog of cysteine with the sulfur-containing side chain replaced by a Se-containing side chain. Sec is encoded by the codon UGA, which is one of three termination codons for mRNA translation in non-selenoprotein genes. Recognition of the UGA codon as a Sec insertion site instead of stop requires a Sec insertion sequence (SECIS) element in selenoprotein mRNAs and a unique selenocysteyl-tRNA, both of which are recognized by specialized protein factors. Unlike the 20 standard amino acids, Sec is biosynthesized from serine on its tRNA. Twenty-five selenoproteins are encoded in the human genome. Most of the selenoprotein genes were discovered by bioinformatics approaches, searching for SECIS elements downstream of in-frame UGA codons. Sec has been described as having stronger nucleophilic and electrophilic properties than cysteine, and Sec is present in the catalytic site of all selenoenzymes. Most selenoproteins, whose functions are known, are involved in redox systems and signaling pathways. However, several selenoproteins are not well characterized in terms of their function. The selenium field has grown dramatically in the last few decades, and research on selenium biology is providing extensive new information regarding its importance for human health.

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“…Some vegetables can grow under selenium-rich soil and accumulate selenium (onions, leeks, garlic, and broccoli) [205]. These vegetables accumulate selenium up to 50-fold or higher.…”

Section: Health Benefits Of Selenium In Humansmentioning

confidence: 99%

Selenium. Role of the Essential Metalloid in Health

Kurokawa

Berry

2013

Metal Ions in Life Sciences

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“…There are several ways to detect nonvolatile selenium compounds, oxyanions, or Se in undetermined chemical forms. 36 From probably most common to least in the recent literature these methods are hydride generation atomic absorption spectrom-etrysHGAAS, [37][38][39][40][41][42][43][44] ICP or ICP/MS, 45,46 normal AAS, 47 LC/ion chromatography, 48,49 fluorometry, [50][51][52][53] X-ray absorption or fluorescence, 32,[54][55][56][57] and neutron activation analysis. 58 Mixtures of selenite, selenate, and selenium containing amino acids present a particularly onerous analytical task.…”

Section: Nonvolatile Selenium Compoundsmentioning

confidence: 99%

“…There are several ways to detect nonvolatile selenium compounds, oxyanions, or Se in undetermined chemical forms . From probably most common to least in the recent literature these methods are hydride generation atomic absorption spectrometryHGAAS, − ICP or ICP/MS, , normal AAS, LC/ion chromatography, , fluorometry, − X-ray absorption or fluorescence, ,− and neutron activation analysis…”

Section: Nonvolatile Selenium Compoundsmentioning

confidence: 99%

Biomethylation of Selenium and Tellurium: Microorganisms and Plants

2002

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“…The emission of various volatile sulfur and selenium species from plants is important since certain plants can take up these elements from the growth medium and, through several biochemical steps, transform them to volatile species. − This phenomenon is called phytovolatilization and may be a part of the mechanism governing phytoremediation, important for its potential in cleaning polluted sites. Understanding various biotransformation processes for sulfur and selenium in plants is useful in attempting to make the phytoremediation techniques more effective.…”

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confidence: 99%

Simultaneous Monitoring of Volatile Selenium and Sulfur Species from Se Accumulating Plants (Wild Type and Genetically Modified) by GC/MS and GC/ICPMS Using Solid-Phase Microextraction for Sample Introduction

et al. 2002

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A sensitive method for determining ultratrace volatile Se species produced from Brassica juncea seedlings is described. The use of a new commercially available GC/ ICPMS interface in conjunction with solid-phase micro-extraction is a promising way to perform these studies. The addition of optional gases (O2 and N2) to the argon discharge proved to increase the sensitivity for Se and S as well as for Xe, which as a trace contaminant gas, was used for ICPMS optimization studies. However, the optimization parameters differ when an optional gas is added. In the best conditions, limits of detection ranging from 1 to 10 ppt can be obtained depending on the Se compound and 30 to 300 ppt for the volatile S species. The use of GC/MS with similar sample introduction permits the characterization of several unknown species produced as artifacts from the standards. The method allows the virtually simultaneous monitoring of S and Se species from the headspace of several plants (e.g., onions, garlic, etc.) although the present work is focused on the B. juncea seedlings grown in closed vials and treated with Se. Dimethyl selenide and dimethyl diselenide were detected as the primary volatile Se components in the headspace. Sulfur species also were present as allyl (2-propenyl) isothiocyanate and 3-butenyl isothiocyanate as characterized by GC/MS.

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The identification of selenium species in biological samples

Cited by 21 publications

References 128 publications

Selenium. Role of the Essential Metalloid in Health

Selenium. Role of the Essential Metalloid in Health

Biomethylation of Selenium and Tellurium: Microorganisms and Plants

Simultaneous Monitoring of Volatile Selenium and Sulfur Species from Se Accumulating Plants (Wild Type and Genetically Modified) by GC/MS and GC/ICPMS Using Solid-Phase Microextraction for Sample Introduction

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