“…Visceral pain, a major symptom in medicine, is typically referred to somatic structures, mostly the muscle, where most frequently secondary hyperalgesia occurs, as revealed by lowered pain thresholds to different stimuli (Arendt‐Nielsen et al, ; Aziz et al, ; Giamberardino, Affaitati, & Costantini, ; Giamberardino, Affaitati, & Costantini, ; Giamberardino & Vecchiet, ; Jarrell, Giamberardino, Robert, & Nasr‐Esfahani, ; Jarrell et al, ; Treede et al, ). Visceral pain syndromes very frequently co‐occur in the same patients and when two viscera are affected, sharing at least part of their central sensory projection, an enhancement of spontaneous pain and referred hyperalgesia from both viscera occur (viscero‐visceral hyperalgesia‐VVH), a phenomenon mainly attributed to sensitization of viscero‐viscero‐somatic convergent neurons whereby nociceptive inputs from one visceral organ enhance the central responses to inputs from the second organ and somatic area of referral (Brumovsky & Gebhart, ; Frøkjaer et al, ; Giamberardino, ; Giamberardino, Costantini, et al, ; Giamberardino et al, ; ; Iuvone et al, ; Lopopolo et al, ; Malykhina, ; Marson, Giamberardino, Costantini, Czakanski, & Wesselmann, ).…”