The
Shigella flexneri
virulence factor apyrase is released inside eukaryotic cells to hijack host cell fate
Lisa Perruzza,
Carlo Zagaglia,
Laura Vitiello
et al.
Abstract:Intestinal epithelial cells represent the first line of defense from invading enteric pathogens. During the course of infection, pro-inflammatory programmed cell death is an effective way to eliminate invading microbes and to create a localized inflammatory environment. On the other hand, pathogens evolved countless strategies to overcome cell death and to keep the host alive ensuring their spread. It was previously shown that
Shigella flexneri
apyrase interacts with OmpA to contribute … Show more
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