Abstract:BackgroundThe current first line drugs for treating uncomplicated malaria are artemisinin (ART) combination therapies. However, Plasmodium falciparum parasites resistant to ART and partner drugs are spreading, which threatens malaria control efforts. Rodent malaria species are useful models for understanding antimalarial resistance, in particular genetic variants responsible for cross resistance to different compounds.MethodsThe Plasmodium berghei RC strain (PbRC) is described as resistant to different antimal… Show more
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