The hydration of phospholipids and phospholipid-cholesterol complexes

Lundberg, Bo; Svens, E.; Ekman, Stig

doi:10.1016/0009-3084(78)90017-8

Cited by 35 publications

(11 citation statements)

References 20 publications

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“…The solubility of phospholipids in water depends on both the head-group polar head type and the hydrocarbon chain length [4,5]. Four classes of phospholipids can be distinguished as a function of PL solubility: class I includes insoluble PLs, that do not absorb water at all (e.g., waxes); class II, PLs with very low solubility, which swell in water (e.g., long-chain phosphatidylcholine, phosphatidylethanolamine or sphingomyelin); class IIIA, soluble PLs forming lyotropic liquid crystals at low water content (e.g., lysolecithins); class IIIB, relatively rare, soluble PLs forming micelles above the critical micelle concentration (cmc), but no crystalline structure (e.g., saponins).…”

Section: Introductionmentioning

confidence: 99%

Phospholipids at the Interface: Current Trends and Challenges

Pichot

Watson

Norton

2013

IJMS

188

113

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Phospholipids are one of the major structural elements of biological membranes. Due to their amphiphilic character, they can adopt various molecular assemblies when dispersed in water, such as bilayer vesicles or micelles, which give them unique interfacial properties and render them very attractive in terms of foam or emulsion stabilization. This article aims at reviewing the properties of phospholipids at the air/water and oil/water interfaces, as well as the recent advances in using these natural components as stabilizers, alone or in combination with other compounds such as proteins. A discussion regarding the challenges and opportunities offered by phospholipids-stabilized structure concludes the review.

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Section: Introductionmentioning

confidence: 99%

Phospholipids at the Interface: Current Trends and Challenges

Pichot

Watson

Norton

2013

IJMS

188

113

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“…The slope, k2, of the line is represented by Eq. 4 (4) Since the solubility of sodium diclofenac is low, it may be estimated that 2A is greater …”

Section: Resultsmentioning

confidence: 99%

Preparation of controlled-release granules of sodium diclofenac.

Hirotani

Arakawa

Maeda

et al. 1987

CHEMICAL & PHARMACEUTICAL BULLETIN

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“…For POPC and EYL, this corresponds to N = 15 and N = 17 (mole water/mole lipid), respectively. The sorption isotherm of DOPC was taken from the literature (Lundberg et al, 1978) and is not as well recorded as the other data sets. It was pointed out by Parsegian et al (1986) that precise water activities above 0.98 are difficult to measure.…”

Section: Resultsmentioning

confidence: 99%

Hydration force parameters of phosphatidylcholine lipid bilayers as determined from 2H-NMR studies of deuterated water

Volke¹,

Eisenblätter²,

Klose³

1994

Biophysical Journal

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The continuous decrease of the quadrupolar splitting of deuterated water interacting with phosphocholine lipid bilayers with growing water concentration is analyzed as a function of the water activity. From the apparent linear dependence on water activity a measure for hydration forces is obtained. The forces calculated are in the range of published data using sorption isotherms and osmotic stress technique in combination with SAXS. A simple interaction potential which includes orientational order of water adsorbed on surfaces gives a physical base for these findings. Therefore, deuterium NMR may become a powerful tool for hydration force analysis complementing well-known methods.

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The hydration of phospholipids and phospholipid-cholesterol complexes

Cited by 35 publications

References 20 publications

Phospholipids at the Interface: Current Trends and Challenges

Phospholipids at the Interface: Current Trends and Challenges

Preparation of controlled-release granules of sodium diclofenac.

Hydration force parameters of phosphatidylcholine lipid bilayers as determined from 2H-NMR studies of deuterated water

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