The hybrid of gold nanoparticles and Ni(OH)2 nanosheet for non-enzymatic glucose sensing in food

Synthesis of Ni-Co Hydroxide Nanosheets Constructed Hollow Cubes for Electrochemical Glucose Determination

“…The increase of peak current upon the addition of glucose suggests an electrochemical catalytic (EC’) electrode process. Thus, the electrode reaction can be summarized as follows [9,35]:Ni0.7Co0.3false(OHfalse)2+OH−→Ni0.7Co0.3OOH+e−+H2normalO; Ni0.7Co0.3OOH+glucose⇌Ni0.7Co0.3false(OHfalse)2+glucolactone; where (1) represents the electrochemical oxidation of Ni 0.7 Co 0.3 (OH) 2 (E), and (2) represents the heterogeneous catalytic process occurring on the surface of the electrode (C’).…”

“…Accordingly, although transition metal hydroxides have been widely explored as electrode materials for nonenzymatic glucose, such as Ni(OH) 2 [9,35,37,38,39,40], Co(OH) 2 [10,38], and Cu(OH) 2 [41,42], the presence of an additional transition metal indeed improved the current density response significantly, which is similar to previous works [43]. As it is shown in the XPS data, the electrode materials displayed both Ni and Co in both +2 and +3 oxidation states.…”

“…Therefore, enzyme-free electrochemical sensors have been developed and have demonstrated excellent sensory performances thanks to their thermal and chemical stability [9,10,11,12,13,14,15,16]. The mechanism of the nonenzymatic glucose sensor is similar to that of the enzymatic catalytic process, which oxidizes glucose to gluconolactone [17,18].…”

Ultrasensitive Detection of a Variety of Analytical Targets Based on a Functionalized Low‐Resistance AuNPs/β‐Ni(OH)2 Nanosheets/Ni Foam Sensing Platform

“…2D layered nanomaterials have recently attracted much attention in the fabrication of miniaturized biosensing devices. The 2D nanostructure with a large fraction of coordinated‐unsaturated surface atoms and chemical active sites is helpful to expedite the charge transfer kinetics and ion diffusion efficiency . Furthermore, the nanothick sheets usually possess obvious structure disorder on their surface, always resulting in a remarkably increased density of states near the Fermi level .…”

“…To address the critical bottleneck described above, nanostructured metals, the work function of those larger than the sum of the bandgap energy and the electron affinity energy of Ni(OH) 2 , can offer various lattices matching with those of electroactive β‐Ni(OH) 2 to produce epitaxial β‐Ni(OH) 2 interfaces and hence make low‐barrier Ohmic contact with a small Schottky barrier 15b,16. Specifically refer to as gold nanoparticles (AuNPs), their excellent biocompatibility and unique properties in the conjugation with biological recognition elements increase their advantages in the field of EIS biosensing applications 11,15a. Inspired by these phenomenon, we demonstrate a miniaturized impedance biosensing electrode based on AuNPs‐electrodeposited β‐Ni(OH) 2 NS/Ni foam nanocomposite, which is tethered with different FNAs to detect a variety of analytical targets with ultrasensitivity, low cost, easy to operation without need of tedious pretreatment.…”