The Humoral Immune Response against Human Endogenous Retroviruses in Celiac Disease: A Case–Control Study
Marco Bo,
Roberto Manetti,
Maria Luigia Biggio
et al.
Abstract:Background: Celiac disease (CD) is an immune-mediated disease characterized by disruptions of the small intestine. Factors such as viral and bacterial infections can trigger CD. Recently, the reactivation of Human Endogenous Retroviruses (HERVs) has also been implicated, but little is known about their specific role in patients with celiac disease. Methods: The purpose of this study is to explore the humoral immune response mounted against epitopes derived from the envelope portion of three families of HERVs (… Show more
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