The Human Ovary and Future of Fertility Assessment in the Post-Genome Era

Abstract

Proteomics has opened up new avenues in the field of gynecology in the post-genome era, making it possible to meet patient needs more effectively and improve their care. This mini-review aims to reveal the scope of proteomic applications through an overview of the technique and its applications in assisted procreation. Some of the latest technologies in this field are described in order to better understand the perspectives of its clinical applications. Proteomics seems destined for a promising future in gynecology, more particularly in relation to the ovary. Nevertheless, we know that reproductive biology proteomics is still in its infancy and major technical and ethical challenges must first be overcome.

Empty Zona Pellucida Only Case: A Critical Review of the Literature

“…"Omics" data are a valuable parameter for embryo selection optimization and promoting personalized IVF treatment [47]. For example, proteomics is an emerging, powerful diagnostic tool, with applications ranging from biomarker identification for effective embryo and oocyte selection and high-risk pregnancy management, to tissue engineering guidance [48]. Another example is transcriptomics; the concept behind this is that gene expression in CCs engulfing the oocyte provides crucial information on the competence of the oocyte itself and, furthermore, the embryo, as these two differential cell-types grow and develop in a highly coordinated and mutually dependent manner.…”