“…Green et al [28] studied a patient with endophthalmitis and found a very high intraocular penetration of amphotericine B. Recently, Records [31] showed that methicillin penetrates intraocularly to give high antibiotic concentrations, whereas the pene tration of this drug in normal eyes is negligible. Further studies by the same author [32] on cephalothin penetration into the aqueous, where he recreated the same blood-aqueous humor barrier condi tion that are seen in inflammed eyes, found a high concentration of the antibiotic in the secondary aqueous humor.…”