The Human Gut Phageome: Identification and Roles in the Diseases

Abstract

The human gut is a complex environment that contains a diversity of microorganisms commonly known as the microbiome. Numerous factors influence the composition of human gut bacterial communities, either contributing to homeostasis or the instability associated with a variety of diseases. In this study, we discuss our understanding that proposes among the most influential factors are likely to be bacteriophages, bacteria-infecting viruses that make up a large percentage of the human gut microbiome, demonstrated to have an association with human health and diseases such as inflammatory bowel disease (IBD), cardiovascular disease (CVD), etc. to provide new therapeutic approaches.