The “honeycomb” gallbladder

Robinson, D.; Oliphant, Michael; Dyer, Raymond B.

doi:10.1007/s00261-018-1850-3

Cited by 3 publications

(4 citation statements)

References 4 publications

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“…Although nonsurgical treatment does not cause trauma, it is difficult to achieve a radical cure. e risk of later recurrence is high [2,3].…”

Section: Prefacementioning

confidence: 99%

The Value of Combined Application of Oxycodone Hydrochloride Injection and Dexmedetomidine in Anesthesia for LC for Patients with Gallbladder Lesions

Wang¹,

Xu²

2021

Journal of Healthcare Engineering

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Objective. To analyze the effect of combined application of oxycodone hydrochloride injection and dexmedetomidine in anesthesia for laparoscopic cholecystectomy (LC) for patients with gallbladder lesions. Method. 93 patients with gallbladder lesions in our hospital were divided into 2 groups by the random number table method. 46 patients in the control group applied oxycodone hydrochloride injection in anesthesia, and 47 patients in the observation group applied oxycodone hydrochloride injection combined with dexmedetomidine in anesthesia. Result. The T1 and T2 MAP levels in the observation group were lower than those in the control group ( P < 0.05 ), and the difference between T3 and the control group was not significantly significant ( P > 0.05 ). The T1 to T3 HR level in the observation group were lower than those in the control group ( P < 0.05 ). The rate of excessive sedation (10.64%) and sedation inefficiency (12.77%) in the observation group was lower than that in the control group (28.26% and 30.43%), and the rate of satisfactory sedation (76.60%) was higher than that in the control group (41.30%) ( P < 0.05 ). The postoperative awakening, tracheal tube removal, and first anal venting time were shorter in the observation group than in the control group ( P < 0.05 ). The WHO scores of incisional pain at 6, 12, 24, and 48 hours after the operation were lower in the observation group than in the control group ( P < 0.05 ). The T2 SOD level in the observation group was higher than that in the control group, and the ROS and MDA levels were lower than those in the control group ( P < 0.05 ). The incidence of side effects of anesthetic in the observation group was 17.02%, which was not statistically different from the control group of 13.04% ( P > 0.05 ). Conclusion. The combined application of oxycodone hydrochloride injection and dexmedetomidine in anesthesia for LC for patients with gallbladder lesions can achieve better sedation and analgesia effect, accelerate postoperative awakening and recovery, and control oxidative stress and fluctuations in signs, without increasing anesthesia-related side effects.

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“…Although nonsurgical treatment does not cause trauma, it is difficult to achieve a radical cure. e risk of later recurrence is high [2,3].…”

Section: Prefacementioning

confidence: 99%

The Value of Combined Application of Oxycodone Hydrochloride Injection and Dexmedetomidine in Anesthesia for LC for Patients with Gallbladder Lesions

Wang¹,

Xu²

2021

Journal of Healthcare Engineering

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“…It's likewise possible to develop a honeycomb gallbladder, possibly as a result of persistent inflammation. It could be congenital or acquired, without symptoms, and found by chance or identified as an outcome of complaints made by the individual [4]. The solid phase of gallbladder advancement, which exists before the third month of fetal growth, is possibly the cause of the septate gallbladder.…”

Section: Discussionmentioning

confidence: 99%

Multi-Septate Gallbladder in a Patient With Acute Cholecystitis

Desai,

Gianchandani

2023

Cureus

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A very uncommon congenital defect called multi-septate gallbladder (MSG) typically results from wrinkling of the gallbladder membrane or insufficient vacuole formation of the growing bud of the gallbladder. The many septa giving MSG its honeycomb appearance cover the whole lumen of the gallbladder. MSG, hyperplastic cholecystitis, and cholecystitis are a few causes of this ultrasonography finding. A large number of patients describe having persistent stomach issues, including discomfort in the epigastrium, and frequent episodes of discomfort in the abdomen with episodes of nausea. The gallbladder's reduced motility is caused by septa, which causes a halt in the passage of bile and may be the cause of persistent stomach discomfort. The purpose of this report is to provide readers with a better knowledge of this ailment and its recommended course of treatment. We are describing a case of a MSG in a 22-year-old patient. We additionally included a few instances for evaluation and analysis. According to the research that is currently accessible, congenital MSG is most likely caused by the gallbladder wall being pushed into its cavity, creating septa that contain muscle fibers. Alternative imaging techniques like magnetic resonance cholangiopancreatography (MRCP) and endoscopic retrograde cholangiopancreatography (ERCP) are the best tools to make the diagnosis. The effectiveness of medical interventions is unknown; however, cholecystectomy has completely resolved symptoms in people.

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“…This wrinkling may result in invaginations of the gallbladder which then merge with intraepithelial tissue [ 2 , 3 ]. Histologically, MSGs have been found to have epithelial layers intermingled with a muscular layer [ 1 , 3 , 7 ].…”

Section: Discussionmentioning

confidence: 99%

“…Due to the limited number of cases reported globally, there are currently no established guidelines on the evaluation and management of MSG. The majority of cases of MSG have been diagnosed on ultrasound; however, this diagnosis has also been made using magnetic resonance cholangiopancreatography and computed tomography [ 1 , 3 , 7 ]. In patients with MSG, it is prudent to rule out other biliary tract abnormalities, particularly those that are at risk for malignant transformation [ 1 ].…”

Section: Discussionmentioning

confidence: 99%