1988
DOI: 10.1016/0361-9230(88)90075-5
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The history of thought concerning the hypothalamus and its functions

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Cited by 41 publications
(12 citation statements)
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“…ASIC1a expression in the amygdala (Coryell et al 2007;Wemmie et al 2003), coupled to the present findings in the SIH and FPT models, may suggest that ASIC1a in the amygdala plays some role in modulating autonomic outflow to other brain areas implicated in the control of autonomic responses to stressful stimuli (Brooks 1988;DiMicco et al 2006;Dimicco and Zaretsky 2007). The therapeutic implications of the present findings suggest that ASIC inhibition may have some clinical relevance since autonomic responses are considered associated features of anxiety disorders (DSM-IV-TR 2000).…”
Section: Discussionmentioning
confidence: 50%
“…ASIC1a expression in the amygdala (Coryell et al 2007;Wemmie et al 2003), coupled to the present findings in the SIH and FPT models, may suggest that ASIC1a in the amygdala plays some role in modulating autonomic outflow to other brain areas implicated in the control of autonomic responses to stressful stimuli (Brooks 1988;DiMicco et al 2006;Dimicco and Zaretsky 2007). The therapeutic implications of the present findings suggest that ASIC inhibition may have some clinical relevance since autonomic responses are considered associated features of anxiety disorders (DSM-IV-TR 2000).…”
Section: Discussionmentioning
confidence: 50%
“…At the turn of the 20th century, there was limited knowledge of the function of this part of the brain surrounding the third ventricle based primarily on various pathological and clinical observations (180). Since then, extensive experimental evidence indicates that the hypothalamus contains the control systems that are critically involved in a wide range of homeostatic and rheostatic regulatory processes (29,185,235). Among these are the control of water balance, food ingestion and energy metabolism, body temperature and neuroendocrine secretion, and regulation of reproduction and various emotional states (76).…”
Section: Central Regions Involved In the Regulation Of Energy Homeostmentioning
confidence: 99%
“…There are multiple neurotransmitters and neuromodulators in hypothalamus (Brooks, 1988). Investigation of the extracellular levels of neurotransmitters and neuromodulators in hypothalamus provides valuable insights into the pathophysiological events that occur during I/R.…”
Section: Introductionmentioning
confidence: 99%