The history of the finding of the house dust mite

Spieksma, F. Th. M.; Dieges, Paul H

doi:10.1016/j.jaci.2003.10.064

Cited by 23 publications

(17 citation statements)

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“…However, if allergy test is positive while no clinical support this is called atopy with no need to give an avoidance advice. 4 Specific IgE tests (sIgE) to diagnose AA are in vivo skin prick test (SPT) and in vitro blood tests. In vivo SPT is the more sensitive than RAST in detecting positive AA ABSTRACT Background: Taif city is an agricultural area with high altitude.…”

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confidence: 99%

Aeroallergens sensitization pattern at Taif city: Saudi

Tayeb

2016

Int J Community Med Public Health

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INTRODUCTIONAllergen is an antigen which can provoke type-I hypersensitivity in which there is an overproduction of immunoglobulin type E (IgE) against this triggering allergen. Source of allergens are food and inhalants mainly. Inhalant allergens are like house dust mites, molds, animals and pollens. 1IgE is an antibody that land over the surface of mast cells in a process called sensitization. With the re-exposure to the same allergen, mast cells explode and release a lot of inflammatory mediators that can start the allergic cascade which is associated with the common allergic disorders. Allergic disorders are like: allergic rhinosinusitis, allergic conjunctivitis, asthma, atopic dermatitis, urticaria and angioedema, food allergy and drug allergy.Unfortunately, many patients with allergies are underdiagnosed. While, others are overdiagnosed and take a lot of unnecessary medications for other diagnosis. Additionally, many patients diagnose allergies by themselves. Hence, performing allergy testing is a crucial step for establishing the triggering factors of these allergic disorders. It's an important practice to connect between the positive allergy test results and the appearance of allergic symptoms immediately after the exposure to allergen. If both are positive this is called an allergy and avoidance advice should be given to patients. However, if allergy test is positive while no clinical support this is called atopy with no need to give an avoidance advice. 4 Specific IgE tests (sIgE) to diagnose AA are in vivo skin prick test (SPT) and in vitro blood tests. In vivo SPT is the more sensitive than RAST in detecting positive AA ABSTRACT Background: Taif city is an agricultural area with high altitude. Sensitization to aeroallergens (AA) in Taif city is not identified. Methods: This study is a retrospective evaluation of a specific IgE (sIgE) blood results to AA of 149 patients. The study group was chosen from all age groups referred to AL BORG laboratory complaining of allergic diseases with expected sensitization to AA in Taif city, starting from January up to December in the year 2013. Results: The commonest AA distributions in Taif city were to indoor AA followed by pollens. The indoor AA is dermatophagoides pteronyssinus 26%, dermatophagoides farina 25%, american cockroach 22% and cat epithelia/hair 21% respectively. While, the pollens are dessert palm pollens 18%, timothy grass 18%, rye grass 17%, bermuda grass 15%, ambrosia 15%, acacia 15%. Conclusions: Indoor followed by pollen AAs are the commonest sensitization pattern at Taif city. This pattern is compatible with worldwide literature except for high percentage of desert palm pollens which is an amazing result that needs a further evaluation.

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confidence: 99%

Aeroallergens sensitization pattern at Taif city: Saudi

Tayeb

2016

Int J Community Med Public Health

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“…House dust mites (HDMs) are important sources of indoor allergens Spieksma and Dieges (2004). Sensitization to HDM in the general population is 9-16% Squillace et al, (1997).…”

Section: Discussionmentioning

confidence: 99%

“…House dust mites (HDM) are major source of inhalant allergens responsible for allergic asthma Spieksma and Dieges, (2004). There are many species of dust mites infested in and around the houses worldwide Dermatophagoides pteronyssinus (Dp) and Dermatophagoides farina (Df) are of the most common house dust mites (HDMs) Arlian and Platts-Mills (2001).…”

Section: Introductionmentioning

confidence: 99%

Allergy to Dermatophagoides pteronyssinus (Der p1) and Dermatophagoides farina (Der f1) in Patients with Atopic Asthma

2015

IJSR

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Background: House dust mites (HDMs) are important sources of indoor allergens. The prevalence of sensitization to HDM in atopic patients is around 70% to 90% worldwide. Objective: Our aim was to measure the specific IgE to components of Der p1and Der f1 in asthmatic patients at Qena Governorate, Egypt. Methods: We performed a prospective evaluation of 48 HDM sensitized asthmatic patients with positive skin prick test to Dermatophagoides pteronyssinus (Der p) and Dermatophagoides farina (Der f). Patients underwent Immuno CAP for specific IgE to Der p 1, Der f 1. Results: Skin prick test were done to 132 patients asthma with attending to Qena University Hospital to Dermatophagoides pteronyssinus (Der p) and Dermatophagoides farina (Der f) and other allergenic components, also skin prick test were done to 38 healthy people as a control group. Skin prick test were positive in 48 patients (36. 36%) (P value is < 0.015). Forty-eight asthmatic patients had detectable serum specific IgE to Der p 1 and Der f 1 by ImmunoCAP assay. There was a significant positive correlation between skin prick test and specific IgE to Der p1 and Der f1 (P value is 0.000).According to sex there was a highly correlation among sensitivity to Der p1 and Der f1 in both males and females (P value is 0.000), also there were a highly significant relation among sensitivity to Der p1 and Der f1(P value is 0.000) and residence (rural r urban)of the studied patients. Conclusion: Sensitization to HDM especially Dermatophagoides pteronyssinus (Der p) and Dermatophagoides farinae (Der f) is similar to previous studies. Determination of Der p 1 and Der f1 specific IgE helps in obtaining additional information in regards to atopic asthma and other allergic diseases.

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“…Estudos mostram que a rinite alérgica, asma brônquica e dermatite atópica são as alergias mais características de atopia (Weiss et al, 1994) (Platts-Mills et al, 1992;Schwarze et al, 1998). Embora componentes orgânicos de diversas origens, tais como esporos de fungos, polens, fibras vegetais, bactérias, restos de alimentos e células epiteliais humanas sejam característicos da poeira, aqueles derivados de artrópodes (ácaros e baratas) representam os principais fatores etiológicos da alergia (Bronswijk et al, 1981;Chew et al, 1999;Arruda et al, 2001;Holt et al, 2005 (Spieksma et al, 2004). Tamanho do corpo ≈ 320µm.…”

Section: Reações De Hipersensibilidade E Alérgenos Ambientaisunclassified

“…FONTE: Spieksma et al, 2004. Estudos epidemiológicos claramente indicam que o Der p pode ser identificado no mundo todo (Fernández-Caldas et al,1993;Montealegre et al, 1997;Rizzo et al, 1997;Serravalle et al, 1999;Nadchatram et al, 2005) e aproximadamente 5 a 10% da população em geral está sensibilizada a este ácaro (Tovey et al, 1981;Henszel et al, 2006 (Sarinho et al, 1996;Geller et al, 1996;Medeiros et al, 1997). O principal alérgeno presente nas fezes do ácaro (Der p 1) é uma enzima proteolítica homóloga a papaína (Chelw et al, 1999), capaz de clivar a ocludina, proteína que compõe as junções compactas localizadas entre as células epiteliais das vias aéreas.…”

Section: Reações De Hipersensibilidade E Alérgenos Ambientaisunclassified

Caracterização quantitativa e funcional da transferência de anticorpos anti-Dermatophagoides pteronyssinus via placenta e colostro materno.

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The history of the finding of the house dust mite

Cited by 23 publications

References 17 publications

Aeroallergens sensitization pattern at Taif city: Saudi

Aeroallergens sensitization pattern at Taif city: Saudi

Allergy to Dermatophagoides pteronyssinus (Der p1) and Dermatophagoides farina (Der f1) in Patients with Atopic Asthma

Caracterização quantitativa e funcional da transferência de anticorpos anti-Dermatophagoides pteronyssinus via placenta e colostro materno.

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