The histological observation of laser biopsy versus scalpel biopsy on plasma cell gingivitis

Abstract

Biopsy is one of the histological diagnostic techniques used to assess cells and tissues to determine the presence and extent of a simple nonneoplastic growth to complicated malignancies. In the oral cavity, there are many techniques available to harvest the tissue, it depends on anatomical location and morphology of the lesion. In which many causes artifacts in the specimen due to poor technique and handling, which can lead to diagnostic pitfalls and misery. Laser is one of the advanced surgical tools used to harvest oral tissue with minimal anesthesia and less discomfort. This was a split-mouth case report conducted on smaller lesion (plasma cell gingivitis) to assess laser and scalpel surgical techniques to determine thermal damage of laser biopsy.

Plasma Cell Gingivitis Treated with Photobiomodulation, with No Recurrence for a Five-Year Follow-Up

“…In differential diagnosis, there are chronic gingivitis non-plaque dependent, atrophic erosive, bullous gingivitis, and possible plasma cell neoplastic infiltrates [ 3 , 4 , 6 ]. Furthermore, PCG could mimic a wide range of life-threatening entities, such as squamous cell carcinoma, autoimmune mucocutaneous bullous diseases, and lymphoproliferative disorders [ 1 , 2 , 4 , 8 , 9 ]. Plasma cell proliferation is also associated with some infectious diseases, such as syphilis [ 2 ], Castleman's disease [ 2 , 10 ], primary infectious disease of the lymph node, and, recently, COVID-19 [ 2 , 11 ].…”