volume 63, issue 1, P23-28 2019
DOI: 10.22336/rjo.2019.5
View full text
|
Sign up to set email alerts
|
Share

Abstract: Objective. We evaluated the histamine’s role in regulating the iris vasomotricity in rats, using as a research tool topical olopatadine, a selective H1 blocker, which is indicated for the treatment of allergic conjunctivitis and ranitidine, a selective H2 blocker mainly used for the treatment of peptic ulcer disease. Methods. Two groups of six Wistar rats anesthetized with ketamine 200 mg/kg body weight were used. They received distilled water in conjunctival instillations, i…

Expand abstract